Devil's Bush
Eleutherococcus senticosus
Eleutherococcus senticosus，又称西伯利亚人参，源自传统东亚医学实践。传统上用于多种用途，包括增强体力和精神表现，但具体使用方法在不同传统中差异很大。 科学研究表明，Eleutheroside B，一种存在于Eleutherococcus senticosus中的化合物，可以通过调节TLR4/MyD88/NF-κB信号通路来缓解小鼠的抑郁样行为。此外，研究表明，Penicillium oxalicum的最佳浓度可以增加Eleutherococcus senticosus叶片中酚类化合物的生物合成，而高浓度可能会抑制代谢物积累。标准化茎提取物还显示出通过调节FoxO3a相关途径减轻地塞米松诱导的骨骼肌萎缩的潜力。 尚未记录有关Eleutherococcus senticosus的重大安全问题，并且文献中没有报告药物相互作用。然而，进一步的研究对于全面了解其在不同背景下的效果和应用是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Eleutheroside B 减轻了由LPS诱导的小鼠抑郁样行为，通过抑制齿状回中的TLR4/MyD88/NF-κB信号通路。
- Eleutherococcus senticosus 维持物种水平的中等遗传多样性，但在种群之间表现出显著差异。
- 研究发现，Penicillium oxalicum 的最佳浓度增强了Eleutherococcus senticosus 叶片中酚类化合物的生物合成，而高浓度则抑制了代谢物积累。
- 标准化的Eleutherococcus senticosus茎提取物通过调节FoxO3a相关途径减轻了地塞米松诱导的大鼠骨骼肌萎缩。
- ESF显著降低了血压并缓解了心脏和肾脏的氧化应激和病理损伤，涉及色氨酸和维生素B6代谢途径的变化。
Frequently asked questions
What is Devil's Bush?
Devil's Bush (Eleutherococcus senticosus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Devil's Bush?
5 sourced findings are recorded for Devil's Bush; the strongest carries evidence grade D. For example: Eleutheroside B 减轻了由LPS诱导的小鼠抑郁样行为，通过抑制齿状回中的TLR4/MyD88/NF-κB信号通路。
How strong is the evidence for Devil's Bush?
The strongest finding for Devil's Bush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Devil's Bush safe? What are the side effects?
No major safety issues are recorded for Devil's Bush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Devil's Bush interact with medications?
No drug interactions are recorded for Devil's Bush in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Devil's Bush?
Devil's Bush is also known as: Элеутерококк колючий.
Is Devil's Bush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Development and Application of EST-SSR Markers to Assess Genetic Diversity and Structure of Eleutherococcus senticosus for Conservation and Breeding. literature abstract metadata
- T2 Integrated network pharmacology and Chinmedomics reveal the molecular mechanisms of aqueous extract of Eleutherococcus senticosus fruit for treating essential hypertension. literature abstract metadata
- T2 Eleutheroside B alleviates LPS-induced depressive-like behaviors by suppressing the TLR4/MyD88/NF-κB signaling pathway in the dentate gyrus. literature abstract metadata
- T2 Unraveling the metabolic regulation of Eleutherococcus senticosus leaves by Penicillium oxalicum: insights from targeted and non-targeted metabolomics. literature abstract metadata
- T2 A standardized Eleutherococcus senticosus stem extract attenuates dexamethasone-induced skeletal muscle atrophy. literature abstract metadata