Common spurge
Euphorbia pekinensis
Euphorbia pekinensis 是一种传统中药植物。虽然其在传统医学中的具体用途尚未详细记录，但研究表明结果令人鼓舞。研究指出，从 Euphorbia pekinensis 中提取的 EP-GA 水凝胶可以在 H22 皮下肝细胞癌（HCC）异种移植模型中抑制肿瘤生长达 68.63%（剂量为 18.75 mg/kg）。此外，从该植物中分离出的两种新化合物显示出对肝细胞癌具有潜在活性且选择性毒性。通过醋、牛奶和 Terminalia chebula 汤剂等加工方法可以减少毒性，这可能是通过改变化学结构或溶解有毒成分来实现的。Euphorbia pekinensis 中的糖鞘脂类物质，包括六碳糖神经酰胺，已被发现可激活肠嗜铬细胞中的 TRPA1，导致 5-HT 分泌增加并可能引起肠道毒性。尚未记录重大安全问题或药物相互作用，但进一步研究对于完全了解其治疗应用和潜在副作用是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，EP-GA 氢凝胶在 H22 皮下肝癌异种移植模型中抑制了 68.63% 的肿瘤生长，剂量为 18.75 mg/kg。
- 来自Euphorbia pekinensis的两种新化合物显示出对肝细胞癌具有选择性细胞毒性的潜在活性。
- 这项研究显示，醋、牛奶和Terminalia chebula煎剂处理可以改变番泻属植物的化学结构或溶解有毒成分从而降低其毒性。
- Euphorbia pekinensis 糖鞘脂，包括六碳糖神经酰胺，激活肠嗜铬细胞的 TRPA1，导致 5- HT 释放增加和肠道毒性。
Frequently asked questions
What is Common spurge?
Common spurge (Euphorbia pekinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common spurge?
4 sourced findings are recorded for Common spurge; the strongest carries evidence grade D. For example: 研究发现，EP-GA 氢凝胶在 H22 皮下肝癌异种移植模型中抑制了 68.63% 的肿瘤生长，剂量为 18.75 mg/kg。
How strong is the evidence for Common spurge?
The strongest finding for Common spurge carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Common spurge safe? What are the side effects?
No major safety issues are recorded for Common spurge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common spurge interact with medications?
No drug interactions are recorded for Common spurge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common spurge?
Common spurge is also known as: Молочай пекинский.
Is Common spurge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 [Common detoxification mechanisms in processing of toxic medicinal herbs of the same genus: a case study of Euphorbia pekinensis, E. ebracteolata, and E. fischeriana]. literature abstract metadata
- T2 Euphorbia pekinensis glycosphingolipids disrupt gut motility and fluid balance via TRPA1 activation in enterochromaffin cells. literature abstract metadata
- T2 Injectable multi-component hydrogel as an inhibitor of choline kinase α achieved the treatment of malignant ascites by inhibiting PI3K/AKT/mTOR signaling pathway. literature abstract metadata
- T2 New terpenoids from Euphorbia pekinensis with potent and selective anti-hepatocellular carcinoma activity. literature abstract metadata