Common spurge
Euphorbia pekinensis
Euphorbia pekinensis，这种植物在传统医学中通常仅少量使用或根本不使用，在科学研究中显示出前景。研究表明其EP-GA水凝胶成分可以抑制H22皮下肝细胞癌（HCC）异种移植模型中的肿瘤生长达68.63%，尽管证据有限且需要进一步的临床试验来证实这些发现。此外，Euphorbia pekinensis 中的两种新化合物显示出对肝细胞癌具有选择性细胞毒性，并可能具有潜在活性，但还需要更多研究以了解其全部治疗意义。该植物中的糖鞘脂如六碳糖神经酰胺可以激活肠嗜铬细胞的TRPA1，导致5-HT释放增加并可能导致肠道功能障碍。通过醋、牛奶或Terminalia chebula煎剂等加工方法可改变化学结构或溶解有毒成分从而降低毒性。Euphorbia pekinensis 没有记录到主要的安全问题或药物相互作用，但鉴于现有数据有限应谨慎使用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，EP-GA 氢凝胶在 H22 皮下肝癌异种移植模型中抑制了 68.63% 的肿瘤生长，剂量为 18.75 mg/kg。
- 来自Euphorbia pekinensis的两种新化合物显示出对肝细胞癌具有选择性细胞毒性的潜在活性。
- 这项研究显示，醋、牛奶和Terminalia chebula煎剂处理可以改变番泻属植物的化学结构或溶解有毒成分从而降低其毒性。
- Euphorbia pekinensis 糖鞘脂，包括六碳糖神经酰胺，激活肠嗜铬细胞的 TRPA1，导致 5- HT 释放增加和肠道毒性。
Frequently asked questions
What is Common spurge?
Common spurge (Euphorbia pekinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common spurge?
4 sourced findings are recorded for Common spurge; the strongest carries evidence grade D. For example: 研究发现，EP-GA 氢凝胶在 H22 皮下肝癌异种移植模型中抑制了 68.63% 的肿瘤生长，剂量为 18.75 mg/kg。
How strong is the evidence for Common spurge?
The strongest finding for Common spurge carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Common spurge safe? What are the side effects?
No major safety issues are recorded for Common spurge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common spurge interact with medications?
No drug interactions are recorded for Common spurge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common spurge?
Common spurge is also known as: Молочай пекинский.
Is Common spurge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 [Common detoxification mechanisms in processing of toxic medicinal herbs of the same genus: a case study of Euphorbia pekinensis, E. ebracteolata, and E. fischeriana]. literature abstract metadata
- T2 Euphorbia pekinensis glycosphingolipids disrupt gut motility and fluid balance via TRPA1 activation in enterochromaffin cells. literature abstract metadata
- T2 Injectable multi-component hydrogel as an inhibitor of choline kinase α achieved the treatment of malignant ascites by inhibiting PI3K/AKT/mTOR signaling pathway. literature abstract metadata
- T2 New terpenoids from Euphorbia pekinensis with potent and selective anti-hepatocellular carcinoma activity. literature abstract metadata