Mangosteen genus
Garcinia
Garcinia 是一种传统上在东南亚各种菜肴和民间医学中使用的植物。尽管其传统的具体用途没有很好地记录，但对其潜在健康益处进行了研究。科学证据表明，Garcinia 种类可以通过与 PRDX1 的共价结合诱导细胞死亡，并影响内质网应激和自噬过程。此外，α-莽草素是 Garcinia 中发现的一种化合物，可以竞争性地与 NDH-2 上的维生素 K 站点结合，从而可能抑制细菌如 S. aureus 电子传递。其他植物来源的生物活性化合物，如番茄红素、异黄酮和科拉维林，在减轻 atrazine 引起的神经毒性方面显示出潜力；然而，需要进一步研究来确认这些发现。尚未识别出重大安全问题或记录在案的药物相互作用与 Garcinia 有关，尽管仍需进行全面的研究以充分了解其效果。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- GA通过与PRDX1的共价结合诱导细胞死亡，调节内质网应激和自噬。
- 该研究修订了泰国三种 Garcinia 种类的分类学，提供了形态描述和保护评估，并指出所有三个种类均产生可食用果实。
- \α-芒果苷与甲萘醌竞争NDH-2的结合位点，阻止金黄色葡萄球菌中醌池中的电子传递。
- 植物来源的生物活性化合物在减轻 atrazine 引起的神经毒性方面显示出前景，但需要进一步的研究。
- 富含多酚的 Garcinia mangostana 果皮提取物改善了高脂饮食和链脲佐菌素诱导的肥胖糖尿病雄性大鼠的新陈代谢和生殖健康。
- BM 显著抑制了结肠癌细胞的增殖并诱导了通过ER应激介导的线粒体功能障碍引起的凋亡。
Frequently asked questions
What is Mangosteen genus?
Mangosteen genus (Garcinia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mangosteen genus?
6 sourced findings are recorded for Mangosteen genus; the strongest carries evidence grade D. For example: GA通过与PRDX1的共价结合诱导细胞死亡，调节内质网应激和自噬。
How strong is the evidence for Mangosteen genus?
The strongest finding for Mangosteen genus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mangosteen genus safe? What are the side effects?
No major safety issues are recorded for Mangosteen genus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mangosteen genus interact with medications?
No drug interactions are recorded for Mangosteen genus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mangosteen genus?
Mangosteen genus is also known as: гарциния, Garcinie.
Is Mangosteen genus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 α-Mangostin Competing the Menaquinone-Binding Sites of NDH-2 to Block the Electron Transfer at the Quinone Pool of Staphylococcus aureus. literature abstract metadata
- T2 Taxonomic treatment of three Thai Garcinia species (section Brindonia, Clusiaceae), with six lectotypifications and conservation status assessments. literature abstract metadata
- T2 Gambogic acid induces cell death via covalent binding with PRDX1 to regulate ER stress and autophagy. literature abstract metadata
- T2 Polyphenol-Rich Mangosteen Pericarp Extract Attenuates Metabolic and Reproductive Dysfunction in High-fat Diet and Streptozotocin-induced Obese-Diabetic Male Rats: A Preliminary Study. literature abstract metadata
- T2 Therapeutic role of plant bioactive compounds in atrazine-mediated neurotoxicity. literature abstract metadata
- T2 β-mangostin triggers ER stress-mediated mitochondrial dysfunction to induce apoptosis in colorectal cancer. literature abstract metadata