Mangosteen genus
Garcinia
Garcinia is a plant traditionally used in various Southeast Asian cuisines and folk medicine. While specific traditional uses are not well-documented, it has been recognized for its culinary value and some medicinal applications. Scientific evidence suggests that compounds within Garcinia, such as α-mangostin, may have potential anti-inflammatory and neuroprotective effects, though the findings are preliminary and require further investigation. The study also revises the taxonomy of three Garcinia species in Thailand, offering morphological descriptions and conservation assessments, noting that all produce edible fruits. In terms of safety, no significant issues have been reported, and there are currently no recorded drug interactions associated with Garcinia use.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- GA induces cell death via covalent binding with PRDX1, regulating ER stress and autophagy.
- The study revises the taxonomy of three Garcinia species in Thailand, providing morphological descriptions and conservation assessments, with all three producing edible fruits.
- α-Mangostin competes with menaquinone for binding sites on NDH-2, blocking electron transfer at the quinone pool in S. aureus.
- Plant-derived bioactive compounds show promise in mitigating atrazine-induced neurotoxicity, but further research is needed.
- A polyphenol-rich Garcinia mangostana pericarp extract improved metabolic and reproductive health in high-fat diet and streptozotocin-induced obese-diabetic male rats.
- BM significantly inhibited colorectal cancer cell proliferation and induced apoptosis through ER stress-mediated mitochondrial dysfunction.
Frequently asked questions
What is Mangosteen genus?
Mangosteen genus (Garcinia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mangosteen genus?
6 sourced findings are recorded for Mangosteen genus; the strongest carries evidence grade D. For example: GA induces cell death via covalent binding with PRDX1, regulating ER stress and autophagy.
How strong is the evidence for Mangosteen genus?
The strongest finding for Mangosteen genus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mangosteen genus safe? What are the side effects?
No major safety issues are recorded for Mangosteen genus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mangosteen genus interact with medications?
No drug interactions are recorded for Mangosteen genus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mangosteen genus?
Mangosteen genus is also known as: гарциния, Garcinie.
Is Mangosteen genus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 α-Mangostin Competing the Menaquinone-Binding Sites of NDH-2 to Block the Electron Transfer at the Quinone Pool of Staphylococcus aureus. literature abstract metadata
- T2 Taxonomic treatment of three Thai Garcinia species (section Brindonia, Clusiaceae), with six lectotypifications and conservation status assessments. literature abstract metadata
- T2 Gambogic acid induces cell death via covalent binding with PRDX1 to regulate ER stress and autophagy. literature abstract metadata
- T2 Polyphenol-Rich Mangosteen Pericarp Extract Attenuates Metabolic and Reproductive Dysfunction in High-fat Diet and Streptozotocin-induced Obese-Diabetic Male Rats: A Preliminary Study. literature abstract metadata
- T2 Therapeutic role of plant bioactive compounds in atrazine-mediated neurotoxicity. literature abstract metadata
- T2 β-mangostin triggers ER stress-mediated mitochondrial dysfunction to induce apoptosis in colorectal cancer. literature abstract metadata