Goa-butter
Garcinia indica
Garcinia indica，也称为kokum，是一种传统植物，在印度和斯里兰卡的烹饪中主要使用。尽管其在传统医学中的应用记录不多，但研究表明它可能具有改善记忆功能和神经保护的作用，通过抑制HAT酶。此外，来自 Garcinia indica 的 Garcinol 在减轻果蝇模型中的类似阿尔茨海默病症状方面显示出前景，通过调节氧化应激、乙酰胆碱酯酶（AChE）活性和促炎细胞因子。此外，有证据表明，Garcinol 可能具有作为表观遗传学调节剂的抗癌特性；然而，需要更多的人类研究来证实这些发现。在安全性方面，尚未记录重大问题，并且目前没有已知与 Garcinia indica 的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究表明，来自 Garcinia indica 的 Garcinol 可能通过抑制 HAT 酶来潜在地改善记忆功能和神经保护。
- 从印度 Garcinia 中提取的 garciniol 在果蝇 Drosophila melanogaster 中显示出减轻类似阿尔茨海默病的神经退行性病变的潜力，通过调节氧化应激、AChE 活性和促炎细胞因子。
- 从 Garcinia indica 提取的 garciniol 展现出作为表观遗传调节剂和抗癌活性的潜力，但需要进一步的人体研究。
- 将虾青素和木荚豆联合补充到饮食诱导的NAFLD小鼠模型中，调节了氧化还原状态和溶酶体降解。
Frequently asked questions
What is Goa-butter?
Goa-butter (Garcinia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Goa-butter?
4 sourced findings are recorded for Goa-butter; the strongest carries evidence grade D. For example: 研究表明，来自 Garcinia indica 的 Garcinol 可能通过抑制 HAT 酶来潜在地改善记忆功能和神经保护。
How strong is the evidence for Goa-butter?
The strongest finding for Goa-butter carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Goa-butter safe? What are the side effects?
No major safety issues are recorded for Goa-butter in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Goa-butter interact with medications?
No drug interactions are recorded for Goa-butter in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Goa-butter?
Goa-butter is also known as: гарциния индийская.
Is Goa-butter a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. literature abstract metadata
- T2 Antioxidant Intervention in NAFLD: Astaxanthin and Kokum Modulate Redox Status and Lysosomal Degradation. literature abstract metadata
- T2 Protective effects of the natural polyphenol garcinol from Garcinia indica mitigates aluminium chloride-induced Alzheimer's-like neurodegeneration in Drosophila melanogaster. literature abstract metadata
- T2 Epigenetic Modulation Is a Key Mechanism in Cognitive Deficit: Unveiling Garcinol as a Potent HAT Inhibitor in Improving Alzheimer's Disease. literature abstract metadata