Gamboge
Garcinia mangostana
Garcinia mangostana，又称山竹，是一种热带常绿树，原产于东南亚。传统上，其用途在任何特定的医学传统中都没有很好地记录下来。然而，一些科学研究表明可能有潜在的健康益处。有限的临床证据表明，山竹果皮提取物可能会改善2型糖尿病（T2DM）患者的胰岛素敏感性和空腹血糖水平，尽管需要更多的研究来证实这些发现。此外，BM（芒果苷）通过抑制结肠癌细胞增殖和通过ER压力介导的线粒体功能障碍诱导凋亡显示出显著的抗肿瘤活性。体外研究表明，α-芒果苷可以通过与NDH-2上的辅酶Q竞争结合位点并阻断电子传递在醌池中抑制金黄色葡萄球菌（Staphylococcus aureus）的生长。富含多酚的山竹果皮提取物还显示出改善肥胖糖尿病雄性大鼠血糖控制、血脂谱和精子质量的效果。迄今为止尚未发现重大安全问题或记录药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- A polyphenol-rich Garcinia mangostana pericarp extract improved metabolic and reproductive health in obese-diabetic male rats.
- 有限的临床证据表明，芒果果皮提取物可能改善2型糖尿病患者的胰岛素敏感性和空腹血糖水平，但需要更大规模的研究。
- \α-芒果苷与甲萘醌竞争NDH-2的结合位点，阻止金黄色葡萄球菌中醌池中的电子传递。
- BM significantly inhibited CRC cell proliferation and induced apoptosis through ER stress-mediated mitochondrial dysfunction.
- 使用4%山竹凝胶作为SRP的辅助治疗显示出显著的临床改善和生化变化，尽管异质性限制了可比性。
Frequently asked questions
What is Gamboge?
Gamboge (Garcinia mangostana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gamboge?
5 sourced findings are recorded for Gamboge; the strongest carries evidence grade A. For example: A polyphenol-rich Garcinia mangostana pericarp extract improved metabolic and reproductive health in obese-diabetic male rats.
How strong is the evidence for Gamboge?
The strongest finding for Gamboge carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Gamboge safe? What are the side effects?
No major safety issues are recorded for Gamboge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gamboge interact with medications?
No drug interactions are recorded for Gamboge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gamboge?
Gamboge is also known as: мангостан, Mangoustanier.
Is Gamboge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Impact of Antioxidant Mangosteen on Clinical and Biochemical Parameters of Periodontitis-A Systematic Review. literature abstract metadata
- T2 Effects of Garcinia mangostana Peel Extract on Glycemic Control in Type 2 Diabetes Mellitus: A Systematic Review of Human Studies. literature abstract metadata
- T2 α-Mangostin Competing the Menaquinone-Binding Sites of NDH-2 to Block the Electron Transfer at the Quinone Pool of Staphylococcus aureus. literature abstract metadata
- T2 Polyphenol-Rich Mangosteen Pericarp Extract Attenuates Metabolic and Reproductive Dysfunction in High-fat Diet and Streptozotocin-induced Obese-Diabetic Male Rats: A Preliminary Study. literature abstract metadata
- T2 β-mangostin triggers ER stress-mediated mitochondrial dysfunction to induce apoptosis in colorectal cancer. literature abstract metadata