Gamboge
Garcinia mangostana
Garcinia mangostana，又称山竹，是一种热带常绿树，原产于东南亚。该地区传统医学实践利用植物的不同部分来实现其认为的健康益处，尽管具体的用途尚未得到充分记录。科学证据表明，果皮提取物可能改善肥胖糖尿病雄性大鼠的代谢和生殖健康，这表明在管理与糖尿病相关的状况方面可能存在潜在的好处。有限的临床研究表明，山竹树皮提取物可能会增强2型糖尿病患者的胰岛素敏感性和降低空腹血糖水平，但需要进一步研究来确认这些效果。化合物BM通过抑制结肠直肠癌细胞增殖并诱导由内质网压力介导的线粒体功能障碍引起的凋亡显示出抗癌作用。此外，在山竹中发现的α-山竹苷与NDH-2上的维生素K竞争结合位点，可能影响细菌如金黄色葡萄球菌中的电子传递过程。迄今为止尚未识别出重大安全问题或药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 富含多酚的 Garcinia mangostana 果皮提取物改善了肥胖糖尿病雄性大鼠的新陈代谢和生殖健康。
- 有限的临床证据表明，芒果果皮提取物可能改善2型糖尿病患者的胰岛素敏感性和空腹血糖水平，但需要更大规模的研究。
- \α-芒果苷与甲萘醌竞争NDH-2的结合位点，阻止金黄色葡萄球菌中醌池中的电子传递。
- BM 显著抑制了CRC细胞增殖并诱导凋亡，通过ER应激介导的线粒体功能障碍。
- 使用4%山竹凝胶作为SRP的辅助治疗显示出显著的临床改善和生化变化，尽管异质性限制了可比性。
Frequently asked questions
What is Gamboge?
Gamboge (Garcinia mangostana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gamboge?
5 sourced findings are recorded for Gamboge; the strongest carries evidence grade A. For example: 富含多酚的 Garcinia mangostana 果皮提取物改善了肥胖糖尿病雄性大鼠的新陈代谢和生殖健康。
How strong is the evidence for Gamboge?
The strongest finding for Gamboge carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Gamboge safe? What are the side effects?
No major safety issues are recorded for Gamboge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gamboge interact with medications?
No drug interactions are recorded for Gamboge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gamboge?
Gamboge is also known as: мангостан, Mangoustanier.
Is Gamboge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Impact of Antioxidant Mangosteen on Clinical and Biochemical Parameters of Periodontitis-A Systematic Review. literature abstract metadata
- T2 Effects of Garcinia mangostana Peel Extract on Glycemic Control in Type 2 Diabetes Mellitus: A Systematic Review of Human Studies. literature abstract metadata
- T2 α-Mangostin Competing the Menaquinone-Binding Sites of NDH-2 to Block the Electron Transfer at the Quinone Pool of Staphylococcus aureus. literature abstract metadata
- T2 Polyphenol-Rich Mangosteen Pericarp Extract Attenuates Metabolic and Reproductive Dysfunction in High-fat Diet and Streptozotocin-induced Obese-Diabetic Male Rats: A Preliminary Study. literature abstract metadata
- T2 β-mangostin triggers ER stress-mediated mitochondrial dysfunction to induce apoptosis in colorectal cancer. literature abstract metadata