Hop
Humulus
Humulus，通常称为蛇麻草，是一种传统上与酿酒和传统医学中使用有关的植物。科学研究表明，Humulus lupulus 的提取物可能通过降低尿素、肌酐和尿酸水平等肾损伤标志物来提供肾脏保护作用，并增加如TAC、CAT、SOD 和 GPx 等抗氧化活性，在动物模型中的毒性肾病中有所体现。此外，Humulus scandens 已经在实验室研究中显示出对非小细胞肺癌的抗癌作用，通过抑制 PI3K/Akt 途径，但这些发现目前仅限于实验室研究。作为饲料添加剂，蛇麻草在不同种类的动物中表现出混合结果，并且具有剂量依赖性的不良反应。对于 Humulus 没有记录到主要的安全问题或药物相互作用，但仍需要进一步的研究来全面了解其潜在的应用和风险。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Humulus lupulus 提取物显著降低了四氯化碳诱导的肾毒性大鼠血清尿素、肌酐和尿酸水平以及肾脏 MDA 含量，同时增加了 TAC、CAT、SOD 和 GPx 活性。
- 研究发现大麦花粉株与细菌和鸡细胞之间的相互作用模式存在差异，观察到一些累加性和协同性效应。
- 攀缘蛇麻子抑制了非小细胞肺癌的生长和转移，通过抑制PI3K/Akt途径。
- 啤酒花作为不同动物种类的饲料添加剂显示出不同的效果，既有某些益处但也存在剂量依赖性的不良影响。
- 补充香浓胡莫酚与次级胆酸减少和IL-10增加相关，可能改善克罗恩病患者的症状。
- GWAS 没有鉴定出显著的 SNP，但发现了几个候选位点，包括一个与细胞壁相关的激酶，用于抵抗蛇形枯萎病在啤酒花中的发生。
Frequently asked questions
What is Hop?
Hop (Humulus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hop?
6 sourced findings are recorded for Hop; the strongest carries evidence grade B. For example: Humulus lupulus 提取物显著降低了四氯化碳诱导的肾毒性大鼠血清尿素、肌酐和尿酸水平以及肾脏 MDA 含量，同时增加了 TAC、CAT、SOD 和 GPx 活性。
How strong is the evidence for Hop?
The strongest finding for Hop carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Hop safe? What are the side effects?
No major safety issues are recorded for Hop in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hop interact with medications?
No drug interactions are recorded for Hop in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hop?
Hop is also known as: Хмель, Houblon.
Is Hop a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Modulation of Microbiota-Derived Bile Acids Linked to Symptom Amelioration in Crohn's Disease: Insights From a Randomized Clinical Trial With Xanthohumol Supplementation. literature abstract metadata
- T2 The potential of Humulus scandens in delaying non-small cell lung cancer: Targeting the PI3K/Akt signaling pathway to inhibit tumor growth and metastasis. literature abstract metadata
- T2 Mixture dependent correlation patterns in antibacterial and cytotoxic activities of five hop isolates. literature abstract metadata
- T2 Protective Effects of Humulus lupulus L. Extract on CCl₄-Induced Nephrotoxicity in Rats. literature abstract metadata
- T2 Association-Based Analysis of Verticillium Wilt Resistance in a Bi-Parental Hop (Humulus lupulus L.) Population for Marker Development in Breeding. literature abstract metadata
- T2 Humulus lupulus L. in Animal Nutrition: Phytochemical Profile, Bioactive Properties, and Applications as a Functional Feed Additive-A Comprehensive Review. literature abstract metadata