Bine

Humulus lupulus, commonly known as hops, is a traditional plant used primarily for brewing beer. While its use in traditional medicine has not been extensively documented, it has shown potential in various scientific studies. In adults with Crohn's disease, xanthohumol at 24 mg/day was well-tolerated and demonstrated minor beneficial trends regarding body mass index (BMI) and gamma-glutamyl transferase (GGT). Hops have also been explored as feed additives for different animal species, showing variable effects; while some benefits were observed, there were also dose-dependent adverse impacts. Genome-wide association studies (GWAS) did not identify significant single nucleotide polymorphisms (SNPs), but found several candidate loci, including a wall-associated kinase, associated with resistance to Verticillium wilt in hop plants. In a study using CCl₄-induced nephrotoxicity rats, Humulus lupulus extract significantly reduced serum urea and creatinine levels, decreased uric acid, and increased antioxidant activities such as TAC, CAT, SOD, and GPx. Safety concerns for Humulus lupulus are minimal based on current data. There have been no major issues recorded regarding its use. Similarly, there is currently no evidence of significant drug interactions associated with this plant.

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