Bine
Humulus lupulus
Humulus lupulus，通常称为蛇麻花，是一种传统植物，主要用于酿造啤酒，并且在草药医学中具有一定的历史用途。它传统上用于帮助睡眠和放松，但没有特定的文献记录表明其在各种传统中的具体应用。科学证据表明，xanthohumol 这种存在于蛇麻花中的化合物，在每天 24 毫克的剂量下被良好耐受，并且显示出对成人克罗恩病患者的体重指数（BMI）和谷氨酰转肽酶（GGT）水平有轻微有益的趋势。此外，蛇麻花提取物在四氯化碳诱导的肾毒性小鼠中显著降低了血清尿素、肌酐、尿酸水平以及肾内丙二醛（MDA），同时增加了总抗氧化能力（TAC）、过氧化氢酶（CAT）、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GPx）的抗氧化活性。然而，证据有限，需要进一步的研究来确认这些发现。蛇麻花没有记录到严重的安全问题或药物相互作用，但还需要更多的研究来全面了解其潜在效果及其应用。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 在每天24毫克的剂量下，香浓胡莫洛尔被很好地耐受，并且在BMI和GGT方面显示出轻微有益的趋势，适用于患有克罗恩病的成年人。
- 啤酒花作为不同动物种类的饲料添加剂显示出不同的效果，既有某些益处但也存在剂量依赖性的不良影响。
- GWAS 没有鉴定出显著的 SNP，但发现了几个候选位点，包括一个与细胞壁相关的激酶，用于抵抗蛇形枯萎病在啤酒花中的发生。
- Humulus lupulus 提取物显著降低了四氯化碳诱导的肾毒性大鼠血清尿素、肌酐和尿酸水平以及肾脏 MDA 含量，同时增加了 TAC、CAT、SOD 和 GPx 活性。
- 研究发现大麦花粉株与细菌和鸡细胞之间的相互作用模式存在差异，观察到一些累加性和协同性效应。
- 维什尼科扎摩斯瓦特奥耶（Vishniacozyma victoriae）的挥发性化合物可以诱导啤酒花形成腺毛，其中2-壬酮是关键生物活性成分。
- 补充香浓胡莫酚与次级胆酸减少和IL-10增加相关，可能改善克罗恩病患者的症状。
Frequently asked questions
What is Bine?
Bine (Humulus lupulus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bine?
7 sourced findings are recorded for Bine; the strongest carries evidence grade B. For example: 在每天24毫克的剂量下，香浓胡莫洛尔被很好地耐受，并且在BMI和GGT方面显示出轻微有益的趋势，适用于患有克罗恩病的成年人。
How strong is the evidence for Bine?
The strongest finding for Bine carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Bine safe? What are the side effects?
No major safety issues are recorded for Bine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bine interact with medications?
No drug interactions are recorded for Bine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bine?
Bine is also known as: Хмель обыкновенный, houblon.
Is Bine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Safety and Tolerability of Xanthohumol in Adults With Crohn's Disease: Results of a Triple-Masked, Randomized, Placebo-Controlled Phase 2 Trial. literature abstract metadata
- T2 Modulation of Microbiota-Derived Bile Acids Linked to Symptom Amelioration in Crohn's Disease: Insights From a Randomized Clinical Trial With Xanthohumol Supplementation. literature abstract metadata
- T2 Volatile Compounds from Vishniacozyma victoriae Induce Glandular Trichome Development in Humulus lupulus. literature abstract metadata
- T2 Mixture dependent correlation patterns in antibacterial and cytotoxic activities of five hop isolates. literature abstract metadata
- T2 Protective Effects of Humulus lupulus L. Extract on CCl₄-Induced Nephrotoxicity in Rats. literature abstract metadata
- T2 Association-Based Analysis of Verticillium Wilt Resistance in a Bi-Parental Hop (Humulus lupulus L.) Population for Marker Development in Breeding. literature abstract metadata
- T2 Humulus lupulus L. in Animal Nutrition: Phytochemical Profile, Bioactive Properties, and Applications as a Functional Feed Additive-A Comprehensive Review. literature abstract metadata