Bine
Humulus lupulus
啤酒花（Humulus lupulus）是一种开花植物，在各种传统草药疗法中占据重要地位。历史上，它被用作镇静剂、安眠剂和利尿剂，以治疗神经系统疾病、失眠、感染和炎症。关于其疗效的科学证据有限且结果不一。虽然黄酮类化合物在某些克罗恩病患者中显示出对体重指数（BMI）和谷氨酰转移酶（GGT）有轻微的积极影响，但动物研究表明，它既有潜在的益处，也有剂量相关的副作用。在动物模型中，提取物似乎可以减少某些肾毒性指标。尚未记录任何重大的安全问题或明显的药物相互作用。
- 传统用于
- 镇静的 · 利尿剂
- 传统体系
- 西方植物疗法 · 传统 · 中医
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
传统用途
科学怎么说
- 在每天24毫克的剂量下，香浓胡莫洛尔被很好地耐受，并且在BMI和GGT方面显示出轻微有益的趋势，适用于患有克罗恩病的成年人。
- 啤酒花作为不同动物种类的饲料添加剂显示出不同的效果，既有某些益处但也存在剂量依赖性的不良影响。
- GWAS 没有鉴定出显著的 SNP，但发现了几个候选位点，包括一个与细胞壁相关的激酶，用于抵抗蛇形枯萎病在啤酒花中的发生。
- Humulus lupulus 提取物显著降低了四氯化碳诱导的肾毒性大鼠血清尿素、肌酐和尿酸水平以及肾脏 MDA 含量，同时增加了 TAC、CAT、SOD 和 GPx 活性。
- 研究发现大麦花粉株与细菌和鸡细胞之间的相互作用模式存在差异，观察到一些累加性和协同性效应。
- 维什尼科扎摩斯瓦特奥耶（Vishniacozyma victoriae）的挥发性化合物可以诱导啤酒花形成腺毛，其中2-壬酮是关键生物活性成分。
- 补充香浓胡莫酚与次级胆酸减少和IL-10增加相关，可能改善克罗恩病患者的症状。
Frequently asked questions
What is Bine?
Bine (Humulus lupulus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Bine traditionally used for?
Traditional sources record Bine for: 镇静的, 利尿剂, 失眠, 感染, 驱虫药, 镇痛药. This reflects traditional use, not a proven medical treatment.
Which traditions use Bine?
Bine appears in these traditions in our sources: Western phytotherapy, traditional, TCM.
What does the scientific evidence say about Bine?
7 sourced findings are recorded for Bine; the strongest carries evidence grade B. For example: 在每天24毫克的剂量下，香浓胡莫洛尔被很好地耐受，并且在BMI和GGT方面显示出轻微有益的趋势，适用于患有克罗恩病的成年人。
How strong is the evidence for Bine?
The strongest finding for Bine carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Bine safe? What are the side effects?
No major safety issues are recorded for Bine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bine interact with medications?
No drug interactions are recorded for Bine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bine?
Bine is also known as: Хмель обыкновенный, houblon.
Is Bine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Safety and Tolerability of Xanthohumol in Adults With Crohn's Disease: Results of a Triple-Masked, Randomized, Placebo-Controlled Phase 2 Trial. literature abstract metadata
- T2 Modulation of Microbiota-Derived Bile Acids Linked to Symptom Amelioration in Crohn's Disease: Insights From a Randomized Clinical Trial With Xanthohumol Supplementation. literature abstract metadata
- T2 Volatile Compounds from Vishniacozyma victoriae Induce Glandular Trichome Development in Humulus lupulus. literature abstract metadata
- T2 Mixture dependent correlation patterns in antibacterial and cytotoxic activities of five hop isolates. literature abstract metadata
- T2 Protective Effects of Humulus lupulus L. Extract on CCl₄-Induced Nephrotoxicity in Rats. literature abstract metadata
- T2 Association-Based Analysis of Verticillium Wilt Resistance in a Bi-Parental Hop (Humulus lupulus L.) Population for Marker Development in Breeding. literature abstract metadata
- T2 Humulus lupulus L. in Animal Nutrition: Phytochemical Profile, Bioactive Properties, and Applications as a Functional Feed Additive-A Comprehensive Review. literature abstract metadata