Balsam Pear
Momordica charantia
Momordica charantia，又称苦瓜或苦冬瓜，是一种传统植物，在各种烹饪和民间医学实践中被使用。这种植物在印度传统医学和中医中传统上用于治疗糖尿病，但其具体用途尚未充分记录。科学研究表明，该植物中的McCIPK6蛋白通过改善ROS清除并激活依赖CBF的信号通路来提高对冷应激的耐受性。此外，还开发了一种LAMP检测方法以识别苦瓜中的Fusarium oxysporum f. sp. momordicae，突显了其在农业应用方面的潜力。从叶片提取物中获得的MAP30显示出显著抑制SK-Hep-1细胞增殖并诱导通过线粒体途径的凋亡，表明可能具有抗肿瘤作用而不影响成纤维细胞。尚未记录到主要的安全问题或药物相互作用，但需要进一步研究以全面了解其潜在益处和应用。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Momordica charantia supplementation was associated with additional improvements in glycemic control compared to continuation of dual antidiabetic therapy alone, primarily affecting HbA1c and fasting plasma glucose.
- 研究发现，McCIPK6 是一种线粒体蛋白，在苦瓜中通过增强ROS清除和激活CBF依赖的冷信号传导途径来正向调节对低温胁迫的耐受性。
- 该研究开发了一种特异性和灵敏性的LAMP检测方法，用于检测苦瓜中是否存在Fusarium oxysporum f. sp. momordicae。
- MAP30 显著抑制了SK-Hep-1细胞增殖并诱导通过线粒体途径的凋亡。
- 高压优化的苦瓜叶提取物显示出增强的植物化学成分、抗氧化活性以及对癌细胞的选择性细胞毒性，而不影响成纤维细胞。
Frequently asked questions
What is Balsam Pear?
Balsam Pear (Momordica charantia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Balsam Pear?
5 sourced findings are recorded for Balsam Pear; the strongest carries evidence grade B. For example: Momordica charantia supplementation was associated with additional improvements in glycemic control compared to continuation of dual antidiabetic therapy alone, primarily affecting HbA1c and fasting plasma glucose.
How strong is the evidence for Balsam Pear?
The strongest finding for Balsam Pear carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Balsam Pear safe? What are the side effects?
No major safety issues are recorded for Balsam Pear in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Balsam Pear interact with medications?
No drug interactions are recorded for Balsam Pear in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Balsam Pear?
Balsam Pear is also known as: момордика харанция.
Is Balsam Pear a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Phytotherapeutic Supplementation with Momordica charantia: Beneficial Effects in Patients with Suboptimal Glycemic Control on Double Antidiabetic Therapy-A Real-World Evidence Observational Study. literature abstract metadata
- T2 MAP30, a type Ⅰ ribosome-inactivating protein, inhibits hepatocellular carcinoma by inducing apoptosis through mitochondria. literature abstract metadata
- T2 Establishment of a Loop-Mediated Isothermal Amplification (LAMP) Method for the Detection of Fusarium oxysporum f. sp. momordicae. literature abstract metadata
- T2 Characterization of McCIPK6, a mitochondrial protein, positively regulating cold stress tolerance in bitter gourd (Momordica charantia L.). literature abstract metadata
- T2 Box-Behnken Design Optimization of High-Pressure Processed Bitter Melon (Momordica charantia) Leaf Extract Enhancing Phytochemicals, Anticancer, and Anti-Inflammatory Activities. literature abstract metadata