Balsam Pear
Momordica cochinchinensis
Momordica cochinchinensis，通常被称为甘果（gac fruit），起源于东南亚，并用于传统医学实践。传统上，它并未广泛记录特定用途；然而，其不同部位在科学研究中显示出潜在益处。水果提取物通过增强HT‑22细胞的突触功能，对β-淀粉样蛋白诱导的毒性提供显著保护，提示可能具有神经保护作用。此外，甲醇提取物展示了对乙酰氨基酚（APAP）诱导肝损伤的肝脏保护特性，通过多种机制实现。更进一步，溶于氯仿-甲醇的部分抑制了口腔鳞状细胞癌（OSCC）细胞在体外的增殖、迁移和侵袭，并通过靶向JAK2/STAT3/c‑Myc通路降低小鼠肿瘤生长。已开发出一种优化工艺，用于获取高纯度Momordica cochinchinensis蛋白浓缩物，可用于功能性食品和补充剂。尚未记录主要安全问题或已知药物相互作用，但仍需进一步研究以充分了解其潜在应用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从木瓜果实部分提取的PE-EtOH和SE-EtOAc对β-淀粉样蛋白诱导的毒性表现出显著的保护作用，通过增强HT-22细胞的突触功能。
- MC 在多种机制下表现出对 APAP 引起的肝损伤的肝保护作用。
- CMSP抑制了OCSC细胞的增殖、迁移和侵袭，并通过靶向JAK2/STAT3/c-Myc途径减少了小鼠肿瘤的生长。
- 该研究开发了一种优化的工艺，用于获得高纯度的Momordica cochinchinensis蛋白质浓缩物，具有独特的性质，可能在功能性食品和补充剂中具有潜在用途。
Frequently asked questions
What is Balsam Pear?
Balsam Pear (Momordica cochinchinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Balsam Pear?
4 sourced findings are recorded for Balsam Pear; the strongest carries evidence grade D. For example: 从木瓜果实部分提取的PE-EtOH和SE-EtOAc对β-淀粉样蛋白诱导的毒性表现出显著的保护作用，通过增强HT-22细胞的突触功能。
How strong is the evidence for Balsam Pear?
The strongest finding for Balsam Pear carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Balsam Pear safe? What are the side effects?
No major safety issues are recorded for Balsam Pear in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Balsam Pear interact with medications?
No drug interactions are recorded for Balsam Pear in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Balsam Pear?
Balsam Pear is also known as: Гак.
Is Balsam Pear a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Hepatoprotective Effects of Gac (Momordica cochinchinensis) Aril Extract in Acetaminophen-Induced Liver Injury: Modulation of Oxidative Stress, Inflammation, and Glucose Metabolism. literature abstract metadata
- T2 CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis. literature abstract metadata
- T2 Neuroprotective Effect of Fresh Gac Fruit Parts Against β-Amyloid-Induced Toxicity and Its Influence on Synaptic Gene Expression in HT-22 Cell Model. literature abstract metadata
- T2 Production, characterization, and functional properties of protein concentrate from Momordica cochinchinensis seeds. literature abstract metadata