Balsam Pear
Momordica cochinchinensis
Momordica cochinchinensis，又称作gac果，起源于东南亚的传统医学实践。传统上，它没有被广泛记录用于特定用途；然而，在各种科学研究中其部分显示出潜力。从果实提取的PE-EtOH和SE-EtOAc通过增强HT-22细胞的突触功能显著保护了β-Amyloid诱导的毒性，这表明其可能对神经退行性疾病有益。此外，MC在APAP诱导的肝损伤方面表现出肝脏保护作用，通过多种机制实现。另外，CMSP（一种蛋白质浓缩物）抑制了OSCC细胞的增殖、迁移和侵袭，并通过靶向JAK2/STAT3/c-Myc途径减少了小鼠肿瘤的生长，表明其可能具有抗癌性质。安全性概况良好，迄今未记录重大问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从木瓜果实部分提取的PE-EtOH和SE-EtOAc对β-淀粉样蛋白诱导的毒性表现出显著的保护作用，通过增强HT-22细胞的突触功能。
- MC 在多种机制下表现出对 APAP 引起的肝损伤的肝保护作用。
- CMSP抑制了OCSC细胞的增殖、迁移和侵袭，并通过靶向JAK2/STAT3/c-Myc途径减少了小鼠肿瘤的生长。
- 该研究开发了一种优化的工艺，用于获得高纯度的Momordica cochinchinensis蛋白质浓缩物，具有独特的性质，可能在功能性食品和补充剂中具有潜在用途。
Frequently asked questions
What is Balsam Pear?
Balsam Pear (Momordica cochinchinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Balsam Pear?
4 sourced findings are recorded for Balsam Pear; the strongest carries evidence grade D. For example: 从木瓜果实部分提取的PE-EtOH和SE-EtOAc对β-淀粉样蛋白诱导的毒性表现出显著的保护作用，通过增强HT-22细胞的突触功能。
How strong is the evidence for Balsam Pear?
The strongest finding for Balsam Pear carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Balsam Pear safe? What are the side effects?
No major safety issues are recorded for Balsam Pear in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Balsam Pear interact with medications?
No drug interactions are recorded for Balsam Pear in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Balsam Pear?
Balsam Pear is also known as: Гак.
Is Balsam Pear a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Hepatoprotective Effects of Gac (Momordica cochinchinensis) Aril Extract in Acetaminophen-Induced Liver Injury: Modulation of Oxidative Stress, Inflammation, and Glucose Metabolism. literature abstract metadata
- T2 CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis. literature abstract metadata
- T2 Neuroprotective Effect of Fresh Gac Fruit Parts Against β-Amyloid-Induced Toxicity and Its Influence on Synaptic Gene Expression in HT-22 Cell Model. literature abstract metadata
- T2 Production, characterization, and functional properties of protein concentrate from Momordica cochinchinensis seeds. literature abstract metadata