Paeony
Paeonia
白芍，又称白芍药或中国白芍，源自东亚的传统医学实践。传统上用于治疗月经痛和肝脏疾病等多种状况，尽管不同传统的具体用途可能有所不同。科学研究表明，芍药苷可以通过调节miR-145-5p/GOLM1轴抑制前列腺癌的进展，而芍药内酯苷可以增加巨噬细胞中SOCS3的表达，从而在骨关节炎（OA）的小鼠模型中潜在地减少炎症。从白芍乳花品种提取的外泌体显示出改善糖尿病周围神经病变的潜力，通过调节CCL21/CCR7信号传导和减少施万细胞损伤及神经炎症。此外，芍药苷还表现出多种药理作用，包括抗炎、神经保护和肝保护效果，尽管其最佳口服生物利用度仍不确定。尚未记录白芍的重大安全问题或药物相互作用，但进一步研究对于完全了解其潜在益处和局限性是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 白花前胡素通过调节miR-145-5p/GOLM1轴抑制前列腺癌进展。
- 白花前胡素上调巨噬细胞中SOCS3的表达，可能在OA小鼠模型中减少炎症。
- 来源于白芍的外泌体通过调节CCL21/CCR7信号传导、减少施万细胞损伤和神经炎症来改善糖尿病周围神经病变。
- 阿尔比弗林显示出多种药理活性，包括抗炎、神经保护和肝保护作用，但最佳口服生物利用度仍不确定。
- 三个品种‘Red Charm’、‘Bartzella’和‘Sarah Bernhardt’在严重应激条件下显示出更强的相对盐碱耐受性。
- 从牡丹（Paeonia lactiflora）根部分离出三种新型单萜类化合物，并在PC12细胞中显示出对H2O2诱导损伤的显著神经保护作用。
Frequently asked questions
What is Paeony?
Paeony (Paeonia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Paeony?
6 sourced findings are recorded for Paeony; the strongest carries evidence grade D. For example: 白花前胡素通过调节miR-145-5p/GOLM1轴抑制前列腺癌进展。
How strong is the evidence for Paeony?
The strongest finding for Paeony carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Paeony safe? What are the side effects?
No major safety issues are recorded for Paeony in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Paeony interact with medications?
No drug interactions are recorded for Paeony in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Paeony?
Paeony is also known as: Пион, pivoine.
Is Paeony a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Paeonia lactiflora-derived extracellular vesicles ameliorate diabetic peripheral neuropathy by modulating chemokine-guided immune trafficking in peripheral nerves. literature abstract metadata
- T2 Monoterpenoids from the roots of Paeonia lactiflora Pall. and their neuroprotective activity. literature abstract metadata
- T2 Paeoniflorin elevates the expression of SOCS3 in macrophages to prevent MIA-induced osteoarthritis in mice. literature abstract metadata
- T2 Paeonol inhibits prostate cancer progression via the miR-145-5p/GOLM1 axis. literature abstract metadata
- T2 Evaluation and physiological response of peony (Paeonia lactiflora Pall.) under salt stress. literature abstract metadata
- T2 A Review of the Pharmacodynamics and Pharmacokinetics of Albiflorin. literature abstract metadata