Ginseng
Panax
人参属植物包括人参（Panax ginseng）和三七（Panax notoginseng），起源于东亚。传统上，这些植物在中国医学中用于多种目的，如增强活力、改善认知功能和管理糖尿病。虽然没有记录特定的传统用途，但现代科学研究表明，人参属植物中存在的活性成分人参皂苷可能调节包括组蛋白去乙酰化酶（HDACs）、DNA甲基转移酶（DNMTs）和microRNA（miRNAs）在内的表观遗传过程，从而提供多靶点的肿瘤抑制策略。此外，研究还确定了关键转录因子PnMYB38在三七中调节皂苷生物合成的作用，突显其复杂的生化特性。值得注意的是，这些植物没有重大安全问题或已记录的药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 人参皂苷在通过多种途径管理代谢功能障碍相关脂肪肝疾病方面显示出潜力，但缺乏人类临床证据。
- 显微镜检查结合HPLC-UV分析有效地鉴定人参属植物并检测常见掺伪品。
- 人参中的 Ginsenosides 调节包括 HDAC、DNMT 和 microRNA 的表观遗传过程，可能提供一种多靶点策略来抑制肿瘤。
- 研究确定了PnMYB38是甲基茉莉酸诱导人参（Panax notoginseng）皂苷生物合成的关键转录因子。
- PnUGT94Q39中的单点突变使大肠杆菌中从Rh1高效合成人参皂苷Rf成为可能。
- G-Rh2通过调节脂质代谢、肠道微生物群和PI3K/AKT信号通路，改善了大鼠冠状动脉疾病。
- 人参生物活性成分在多种疾病中调节肠-脑轴显示出有希望的前期临床治疗潜力，尽管仍需进一步的临床验证。
- 这项研究发现，各种植物提取物显示出作为心力衰竭辅助疗法的潜力，不同的提取物在改善心脏功能和生活质量方面提供了不同的优势。
- 研究发现，在患有结肠炎的大鼠中，人参皂苷代谢物，尤其是去糖基化产物有显著减少。
- 研究发现，人参中的中性和酸性多糖表现出不同的消化特性，并与肠道微生物相互作用以产生免疫调节效应。
- 在猕猴桃植物中鉴定出一种新的totivirus，Actinidia totivirus 1（AcToV1），并与Panax notoginseng病毒A密切相关。
- 气血回心滴丸通过靶向TGF-β/骨连接蛋白轴减轻由缺血再灌注引起的纤维性心肌损伤。
Frequently asked questions
What is Ginseng?
Ginseng (Panax) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ginseng?
12 sourced findings are recorded for Ginseng; the strongest carries evidence grade A. For example: 人参皂苷在通过多种途径管理代谢功能障碍相关脂肪肝疾病方面显示出潜力，但缺乏人类临床证据。
How strong is the evidence for Ginseng?
The strongest finding for Ginseng carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Ginseng safe? What are the side effects?
No major safety issues are recorded for Ginseng in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ginseng interact with medications?
No drug interactions are recorded for Ginseng in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Ginseng?
Ginseng is also known as: Женьшень.
Is Ginseng a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Protein Engineering to Change the Sugar Donor and Improve the Activity of PnUGT94Q39 for Efficient Ginsenoside Rf Biosynthesis. literature abstract metadata
- T2 The transcription factor PnMYB38 orchestrates methyl jasmonate-induced saponin biosynthesis in Panax notoginseng. literature abstract metadata
- T2 Ginsenosides as epigenetic modulators: HDAC, DNMT, and miRNA-targeted mechanisms in tumour suppression. literature abstract metadata
- T2 Microscopy Combined with LC-UV Analysis as a Tool for Authentication of Ginseng Species Used in Traditional Medicine and Detection of Their Adulterants. literature abstract metadata
- T2 Qishen Yiqi Dripping Pills Alleviate Myocardial Ischemia-Reperfusion-Induced Fibrotic Injury by Inhibiting Fibroblast Activation via the Transforming Growth Factor-Beta/Periostin Pathway. literature abstract metadata
- T2 Genomic characterization of Actinidia totivirus 1 (AcToV1), a novel member of the genus Totivirus infecting kiwifruit. literature abstract metadata
- T2 The neutral and acidic polysaccharides from Ginseng are metabolized by specific gut microbial taxa and confer immunomodulatory effects. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
- T2 Ginsenoside Rh2 Regulates PI3K/AKT Signaling, Metabolic Pathways, and the Gut Microbiota for Coronary Heart Disease Therapy. literature abstract metadata
- T2 Ginseng Bioactive Components as Gut-Brain Axis-Targeted Modulators: Therapeutic Potential and Mechanisms in Multifactorial Diseases. literature abstract metadata
- T2 Ginsenosides for the Management of Metabolic Dysfunction-Associated Fatty Liver Disease: A Research Update. literature abstract metadata
- T2 Metabolic Profiling of Panax notoginseng Saponins in Rat Feces Under Colitis by UHPLC-QTOF-MS/MS. literature abstract metadata