Panax ginseng
Panax ginseng
人参，又称亚洲人参，是一种传统草药，在东亚实践中使用了数个世纪。它通常用于对抗疲劳和作为一般补品。科学证据表明，人参中活性成分人参皂苷可能调节组蛋白去乙酰化酶（HDACs）、DNA甲基转移酶（DNMTs）和微小RNA（miRNAs）等表观遗传过程，从而潜在地抑制肿瘤的发展。此外，这些化合物还可能通过多种途径管理与代谢功能障碍相关的脂肪肝疾病；然而，在这一领域的人类临床证据仍然有限。一项研究指出，PnUGT94Q39中的单点突变使得能够从Rh1在大肠杆菌中高效合成人参皂苷Rf，这表明其可能用于心力衰竭管理，尽管这些证据是混合的且需要进一步验证。
- 传统用于
- 疲劳和一般补品（传统）
- 传统体系
- 中医
- 最佳证据
- A
- 注意事项
- ⚕ 1
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
传统用途
科学怎么说
- 人参中的 Ginsenosides 调节包括 HDAC、DNMT 和 miRNAs 在内的表观遗传过程，可能抑制肿瘤的发生。
- 人参皂苷在通过多种途径管理代谢功能障碍相关脂肪肝疾病方面显示出潜力，但缺乏人类临床证据。
- PnUGT94Q39中的单点突变使大肠杆菌中从Rh1高效合成人参皂苷Rf成为可能。
- 这项研究指出，各种植物提取物，包括人参Panax ginseng，可能为心力衰竭患者提供潜在的好处，尽管证据相互矛盾且需要进一步验证。
- 人参生物活性成分在多种疾病中调节肠-脑轴显示出有希望的前期临床治疗潜力，尽管仍需进一步的临床验证。
- 短期人参补充显著减少了消化道癌症幸存者的疲劳且主要副作用较少。
- 人参在餐前90分钟服用可使健康中年受试者的餐后血糖和胰岛素水平分别降低29%和24%。
药物相互作用
- 华法林 — 可能会降低华法林的抗凝效果
Frequently asked questions
What is Panax ginseng?
Panax ginseng (Panax ginseng) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Panax ginseng traditionally used for?
Traditional sources record Panax ginseng for: 疲劳和一般补品（传统）. This reflects traditional use, not a proven medical treatment.
Which traditions use Panax ginseng?
Panax ginseng appears in these traditions in our sources: TCM.
What does the scientific evidence say about Panax ginseng?
7 sourced findings are recorded for Panax ginseng; the strongest carries evidence grade A. For example: 人参中的 Ginsenosides 调节包括 HDAC、DNMT 和 miRNAs 在内的表观遗传过程，可能抑制肿瘤的发生。
How strong is the evidence for Panax ginseng?
The strongest finding for Panax ginseng carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Panax ginseng safe? What are the side effects?
No major safety issues are recorded for Panax ginseng in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Panax ginseng interact with medications?
Recorded drug interactions for Panax ginseng involve: 华法林. Tell your doctor or pharmacist about any herb you take.
What are the common names of Panax ginseng?
Panax ginseng is also known as: Женьшень обыкновенный.
Is Panax ginseng a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 NCCIH: Asian Ginseng public domain (attribute NCCIH)
- T2 Preload time-dependent effects of Panax ginseng on postprandial glucose tolerance. A randomized controlled study in healthy middle-aged participants. literature abstract metadata
- T2 The effect of ginseng extract on fatigue in cancer survivors: a randomized double-blind clinical trial. literature abstract metadata
- T2 Protein Engineering to Change the Sugar Donor and Improve the Activity of PnUGT94Q39 for Efficient Ginsenoside Rf Biosynthesis. literature abstract metadata
- T2 Ginsenosides as epigenetic modulators: HDAC, DNMT, and miRNA-targeted mechanisms in tumour suppression. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
- T2 Ginseng Bioactive Components as Gut-Brain Axis-Targeted Modulators: Therapeutic Potential and Mechanisms in Multifactorial Diseases. literature abstract metadata
- T2 Ginsenosides for the Management of Metabolic Dysfunction-Associated Fatty Liver Disease: A Research Update. literature abstract metadata