Butterbur

Petasites

Petasites,包括如Petasites japonicus、Dianthus superbus var. superbus和Petasites paradoxus等物种,在各种传统草药实践中被广泛使用,但这些特定物种的具体用途尚未记录。科学证据表明,P. japonicus叶片提取物可能通过多种机制缓解结肠炎症状和抑郁样行为,包括胆碱能功能的恢复以及与神经可塑性相关信号通路的调节。此外,Dianthus superbus var. superbus和Petasites paradoxus的提取物在Chinese Hamster Ovary细胞中表现出剂量依赖性的细胞毒性作用和遗传毒性潜力,而Salvia pratensis叶片提取物通过miR-34a-5p的调控显示出对三阴性乳腺癌细胞的选择性抗肿瘤效应。迄今为止,尚未记录Petasites物种的重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 日本银莲花叶提取物通过多种机制缓解DSS诱导的结肠炎和抑郁样行为。 D PMID
  • PPJM 预处理部分改善了由阿托品诱导的记忆缺陷,并调节了小鼠的胆碱能功能和神经炎症反应。 D PMID
  • Dianthus superbus var. superbus 和 Petasites paradoxus 的甲醇叶提取物在中國地鼠卵巢细胞中表现出剂量依赖性的细胞毒性作用和遗传毒性强势。 D PMID
  • 羊茅叶提取物在通过miR-34a-5p调节作用于三阴性乳腺癌细胞时显示出选择性的抗癌效果。 D PMID

Frequently asked questions

What is Butterbur?

Butterbur (Petasites) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Butterbur?

4 sourced findings are recorded for Butterbur; the strongest carries evidence grade D. For example: 日本银莲花叶提取物通过多种机制缓解DSS诱导的结肠炎和抑郁样行为。

How strong is the evidence for Butterbur?

The strongest finding for Butterbur carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Butterbur safe? What are the side effects?

No major safety issues are recorded for Butterbur in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Butterbur interact with medications?

No drug interactions are recorded for Butterbur in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Butterbur?

Butterbur is also known as: белокопытник, Pétasite.

Is Butterbur a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Salvia pratensis exhibits in vitro anti-cancer effects in triple-negative breast cancer through miR-34a-5p signaling. literature abstract metadata
  2. T2 Petasites japonicus Leaves Alleviate Depression in Dextran Sulfate Sodium-Induced Colitis Mice Through the BDNF/TrkB Pathway and Modulation of Inflammation. literature abstract metadata
  3. T2 Genotoxic potential of Dianthus superbus var. superbus and Petasites paradoxus (Retz.) Baumg. methanolic extracts in Chinese hamster ovary cells. literature abstract metadata
  4. T2 Protective Effects of a Propolis-Petasites japonicus Mixture on Scopolamine-Induced Memory Impairment in Mice. literature abstract metadata