Petasites japonicus
Petasites japonicus
Petasites japonicus，又称日本牛皮菜，是一种传统上在东亚医学中使用的植物。尽管其具体的传统用途没有很好地记录下来，但科学研究表明，其叶片提取物可以缓解小鼠的结肠炎症状和类似抑郁的行为，并通过多种机制发挥作用。此外，PPJM（日本牛皮菜甲醇提取物）被发现能够改善记忆缺陷并调节小鼠的胆碱能功能和神经炎症反应。在一项犬类临床试验中，BSE（牛皮菜根提取物）给药延长了总体生存期，但对口腔黑色素瘤的无进展生存期没有显著影响，并且按照指示使用时表现出安全性。从Petasites japonicus衍生的KP-1外用制剂已被证明可以减少紫外线B诱导的皮肤损伤，通过增加皮肤水分和激活保护性信号通路来实现。尚未记录到重大安全问题或药物相互作用，但需要进一步研究以全面确认这些发现。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 日本银莲花叶提取物通过多种机制缓解DSS诱导的结肠炎和抑郁样行为。
- PPJM 预处理部分改善了由阿托品诱导的记忆缺陷，并调节了小鼠的胆碱能功能和神经炎症反应。
- KP-1 减少了紫外线UVB引起的皮肤损伤，包括皱纹和胶原蛋白降解，同时增强了皮肤保湿并激活了保护性信号通路。
- BSE 的管理显著延长了总体生存期，但并未延长无进展生存期，在患有口腔黑色素瘤的狗中是安全的。
Frequently asked questions
What is Petasites japonicus?
Petasites japonicus (Petasites japonicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Petasites japonicus?
4 sourced findings are recorded for Petasites japonicus; the strongest carries evidence grade D. For example: 日本银莲花叶提取物通过多种机制缓解DSS诱导的结肠炎和抑郁样行为。
How strong is the evidence for Petasites japonicus?
The strongest finding for Petasites japonicus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Petasites japonicus safe? What are the side effects?
No major safety issues are recorded for Petasites japonicus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Petasites japonicus interact with medications?
No drug interactions are recorded for Petasites japonicus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Petasites japonicus?
Petasites japonicus is also known as: Белокопытник японский, Pétasite du Japon.
Is Petasites japonicus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Anti-Photoaging Effects of a Standardized Hot Water Extract of Petasites japonicus Leaves in Ultraviolet B-Exposed Hairless Mice. literature abstract metadata
- T2 Clinical impact of butterbur shoot extract in dogs with oral melanoma: a combined phase 1 and 2 clinical trial. literature abstract metadata
- T2 Petasites japonicus Leaves Alleviate Depression in Dextran Sulfate Sodium-Induced Colitis Mice Through the BDNF/TrkB Pathway and Modulation of Inflammation. literature abstract metadata
- T2 Protective Effects of a Propolis-Petasites japonicus Mixture on Scopolamine-Induced Memory Impairment in Mice. literature abstract metadata