Chinese rhubarb

Rheum palmatum

Rheum palmatum, commonly known as Chinese rhubarb, is a traditional plant used in East Asian medicine. It has been employed for its laxative properties and to treat conditions such as jaundice in various Chinese herbal practices. Scientific evidence suggests that emodin, one of its active compounds, may activate the CFTR chloride channel through a cAMP/PKA pathway-dependent mechanism, potentially explaining its laxative effects. Additionally, there is some indication from a meta-analysis that combining Chinese herbal medicine with Western medicine can improve clinical outcomes in severe acute pancreatitis-related acute lung injury/ARDS; however, more research is needed to confirm these findings. No major safety concerns or drug interactions have been reported for Rheum palmatum.

速览
最佳证据
A
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 大黄素以cAMP/PKA途径依赖的方式激活CFTR氯通道,这表明其泻药作用的机制。 D PMID
  • 该研究回顾了茵陈蒿汤在阻塞性黄疸中的辅助治疗效果和机制,但无明确的健康声明。 D PMID
  • 荟萃分析表明,将中医与西医药物结合使用可显著改善患有SAP-ALI/ARDS患者的临床疗效,尽管存在一些限制。 A PMID
  • 转基因番茄果实表达了来自Rheum palmatum和Rubus idaeus的酶,在成熟过程中产生少量的覆盆子酮苷。 D PMID

Frequently asked questions

What is Chinese rhubarb?

Chinese rhubarb (Rheum palmatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Chinese rhubarb?

4 sourced findings are recorded for Chinese rhubarb; the strongest carries evidence grade A. For example: 大黄素以cAMP/PKA途径依赖的方式激活CFTR氯通道,这表明其泻药作用的机制。

How strong is the evidence for Chinese rhubarb?

The strongest finding for Chinese rhubarb carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Chinese rhubarb safe? What are the side effects?

No major safety issues are recorded for Chinese rhubarb in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Chinese rhubarb interact with medications?

No drug interactions are recorded for Chinese rhubarb in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Chinese rhubarb?

Chinese rhubarb is also known as: Ревень пальчатый, Rhubarbe.

Is Chinese rhubarb a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Assessment of the efficacy of Chinese herbal medicine combined with western medicine for treating severe acute pancreatitis-related acute lung injury/acute respiratory distress syndrome: a systematic review and meta-analysis based on random literature abstract metadata
  2. T2 Exploring the laxative effects of emodin on constipation through chloride channel activation. literature abstract metadata
  3. T2 Metabolic engineering of tomato fruits for production of raspberry ketone glycosides. literature abstract metadata
  4. T2 Adjuvant therapeutic effects and mechanisms of Yinchenhao decoction in obstructive jaundice: a narrative review. literature abstract metadata