Chinese rhubarb
Rheum palmatum
Rheum palmatum，常被称为中国大黄，是一种传统植物，在东亚医学中使用。它已在各种实践中使用了数百年，尤其是在传统中医（TCM）中，人们认为其具有泻药和解毒作用。科学证据表明，其活性成分之一——芦丁能通过cAMP/PKA通路依赖机制激活CFTR氯离子通道，这可能解释了它的一些泻肠效果。此外，有研究指出，银柴胡汤在阻塞性黄疸中的潜在辅助治疗作用，以及与西医联合使用时对重度急性胰腺炎相关肺损伤/急性呼吸窘迫综合征（SAP-ALI/ARDS）患者的临床疗效提升，但证据尚不确定。该植物也被实验用于在转基因番茄果实中产生少量覆盆子酮苷，凸显其传统用途之外的潜在应用。至今未发现Rheum palmatum存在主要安全问题或已记录药物相互作用，但仍需进一步研究以充分了解其治疗和安全特性。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 大黄素以cAMP/PKA途径依赖的方式激活CFTR氯通道，这表明其泻药作用的机制。
- 该研究回顾了茵陈蒿汤在阻塞性黄疸中的辅助治疗效果和机制，但无明确的健康声明。
- 荟萃分析表明，将中医与西医药物结合使用可显著改善患有SAP-ALI/ARDS患者的临床疗效，尽管存在一些限制。
- 转基因番茄果实表达了来自Rheum palmatum和Rubus idaeus的酶，在成熟过程中产生少量的覆盆子酮苷。
Frequently asked questions
What is Chinese rhubarb?
Chinese rhubarb (Rheum palmatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese rhubarb?
4 sourced findings are recorded for Chinese rhubarb; the strongest carries evidence grade A. For example: 大黄素以cAMP/PKA途径依赖的方式激活CFTR氯通道，这表明其泻药作用的机制。
How strong is the evidence for Chinese rhubarb?
The strongest finding for Chinese rhubarb carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese rhubarb safe? What are the side effects?
No major safety issues are recorded for Chinese rhubarb in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese rhubarb interact with medications?
No drug interactions are recorded for Chinese rhubarb in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese rhubarb?
Chinese rhubarb is also known as: Ревень пальчатый, Rhubarbe.
Is Chinese rhubarb a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Assessment of the efficacy of Chinese herbal medicine combined with western medicine for treating severe acute pancreatitis-related acute lung injury/acute respiratory distress syndrome: a systematic review and meta-analysis based on random literature abstract metadata
- T2 Exploring the laxative effects of emodin on constipation through chloride channel activation. literature abstract metadata
- T2 Metabolic engineering of tomato fruits for production of raspberry ketone glycosides. literature abstract metadata
- T2 Adjuvant therapeutic effects and mechanisms of Yinchenhao decoction in obstructive jaundice: a narrative review. literature abstract metadata