Bloodroot
Sanguinaria
Sanguinaria，常被称为血根，起源于北美，并拥有悠久的传统使用历史。虽然其在传统医学中的具体应用尚未得到充分记录，但研究表明它可能具有改善急性肾损伤、降低炎症和氧化应激等潜在益处，以及通过影响膜完整性和IGPD活性，对Staphylococcus aureus具备抗菌特性。科学证据显示，Sanguinaria的主要成分sanguinarine也可能通过调节体外信号通路表现出抗癌作用。然而，由于研究仍属初步，其发现的力度目前有限。尚未报告该植物存在显著安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究鉴定出来自11种传统药用植物的多种植物成分，包括加拿大血草，这些成分通过体外调节关键信号通路显示出潜在的抗癌活性。
- 血根碱通过减轻炎症、氧化应激和细胞损伤，改善了小鼠顺铂诱导的急性肾损伤。
- 血根碱表现出抗菌作用并干扰了金黄色葡萄球菌的生物膜形成，影响了膜完整性及IGPD活性。
- 研究发现，血根碱的肠道吸收显著受P-gp蛋白影响，并涉及多种转运机制。
Frequently asked questions
What is Bloodroot?
Bloodroot (Sanguinaria) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bloodroot?
4 sourced findings are recorded for Bloodroot; the strongest carries evidence grade D. For example: 研究鉴定出来自11种传统药用植物的多种植物成分，包括加拿大血草，这些成分通过体外调节关键信号通路显示出潜在的抗癌活性。
How strong is the evidence for Bloodroot?
The strongest finding for Bloodroot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bloodroot safe? What are the side effects?
No major safety issues are recorded for Bloodroot in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bloodroot interact with medications?
No drug interactions are recorded for Bloodroot in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bloodroot?
Bloodroot is also known as: Сангвинария.
Is Bloodroot a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Studies on pharmacokinetic properties and intestinal absorption mechanism of sanguinarine chloride: in vivo and in situ. literature abstract metadata
- T2 Targeting membrane integrity and imidazoleglycerol-phosphate dehydratase: Sanguinarine multifaceted approach against Staphylococcus aureus biofilms. literature abstract metadata
- T2 Interplay Between Traditional and Scientific Knowledge: Phytoconstituents and Their Roles in Lung and Colorectal Cancer Signaling Pathways. literature abstract metadata
- T2 Attenuation of cisplatin-induced acute kidney injury by sanguinarine: modulation of oxidative stress, inflammation, and cellular damage. literature abstract metadata