Bloodroot

Sanguinaria

Sanguinaria, commonly known as bloodroot, originates from North America and has a long-standing tradition in Native American herbal medicine. Traditionally, it was used for various purposes such as skin treatments and as an expectorant, though specific uses are not well-documented. Scientific evidence suggests that sanguinarine, a key component of Sanguinaria, may have potential therapeutic benefits. Studies indicate that sanguinarine can improve cisplatin-induced acute kidney injury in mice by reducing inflammation, oxidative stress, and cellular damage. Additionally, it has shown antimicrobial properties against Staphylococcus aureus, affecting membrane integrity and IGPD activity, as well as modulating key signaling pathways in lung and colorectal cancer cells. Safety findings are generally positive with no major issues recorded; however, the limited data precludes definitive conclusions. There are currently no reported drug interactions associated with Sanguinaria use.

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究鉴定出来自11种传统药用植物的多种植物成分,包括加拿大血草,这些成分通过体外调节关键信号通路显示出潜在的抗癌活性。 D PMID
  • 血根碱通过减轻炎症、氧化应激和细胞损伤,改善了小鼠顺铂诱导的急性肾损伤。 D PMID
  • 血根碱表现出抗菌作用并干扰了金黄色葡萄球菌的生物膜形成,影响了膜完整性及IGPD活性。 D PMID
  • 研究发现,血根碱的肠道吸收显著受P-gp蛋白影响,并涉及多种转运机制。 D PMID

Frequently asked questions

What is Bloodroot?

Bloodroot (Sanguinaria) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Bloodroot?

4 sourced findings are recorded for Bloodroot; the strongest carries evidence grade D. For example: 研究鉴定出来自11种传统药用植物的多种植物成分,包括加拿大血草,这些成分通过体外调节关键信号通路显示出潜在的抗癌活性。

How strong is the evidence for Bloodroot?

The strongest finding for Bloodroot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Bloodroot safe? What are the side effects?

No major safety issues are recorded for Bloodroot in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Bloodroot interact with medications?

No drug interactions are recorded for Bloodroot in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Bloodroot?

Bloodroot is also known as: Сангвинария.

Is Bloodroot a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Studies on pharmacokinetic properties and intestinal absorption mechanism of sanguinarine chloride: in vivo and in situ. literature abstract metadata
  2. T2 Targeting membrane integrity and imidazoleglycerol-phosphate dehydratase: Sanguinarine multifaceted approach against Staphylococcus aureus biofilms. literature abstract metadata
  3. T2 Interplay Between Traditional and Scientific Knowledge: Phytoconstituents and Their Roles in Lung and Colorectal Cancer Signaling Pathways. literature abstract metadata
  4. T2 Attenuation of cisplatin-induced acute kidney injury by sanguinarine: modulation of oxidative stress, inflammation, and cellular damage. literature abstract metadata