Buerger’s figwort
Scrophularia buergeriana
Scrophularia buergeriana, a plant native to East Asia, has not been traditionally used in any known medicinal practices. Scientific evidence suggests that an extract from this plant may have potential benefits for cognitive function and neuroprotection, as observed in studies where it mitigated scopolamine-induced cognitive impairment in mice and showed estrogen-like activity by promoting cell proliferation and increasing ERα expression. However, the strength of these findings is limited due to the lack of human clinical trials and specific dosing recommendations. No major safety concerns or drug interactions have been recorded for Scrophularia buergeriana; however, further research is needed to fully understand its potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that an extract of Scrophularia buergeriana showed potential in mitigating scopolamine-induced cognitive impairment in mice, with identified metabolic changes in the cortex and hippocampus.
- Scrophularia buergeriana extract reduced neuroinflammation and promoted neuroprotection by modulating signaling pathways in microglia and neurons.
- Brainon® administration improved cognitive deficits and alleviated AD-related pathologies in SAMP8 mice without explicit dosing or treatment recommendations.
- Scrophularia buergeriana root extract showed estrogen-like activity by promoting MCF-7 cell proliferation and increasing ERα expression.
Frequently asked questions
What is Buerger’s figwort?
Buerger’s figwort (Scrophularia buergeriana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Buerger’s figwort?
4 sourced findings are recorded for Buerger’s figwort; the strongest carries evidence grade D. For example: The study found that an extract of Scrophularia buergeriana showed potential in mitigating scopolamine-induced cognitive impairment in mice, with identified metabolic changes in the cortex and hippocampus.
How strong is the evidence for Buerger’s figwort?
The strongest finding for Buerger’s figwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Buerger’s figwort safe? What are the side effects?
No major safety issues are recorded for Buerger’s figwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Buerger’s figwort interact with medications?
No drug interactions are recorded for Buerger’s figwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Buerger’s figwort?
Buerger’s figwort is also known as: Норичник Бюргера.
Is Buerger’s figwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effects of Scrophularia buergeriana Extract (Brainon®) on Aging-Induced Memory Impairment in SAMP8 Mice. literature abstract metadata
- T2 Scrophularia buergeriana Extract (Brainon) Attenuates Neuroinflammation in BV-2 Microglia Cells and Promotes Neuroprotection in SH-SY5Y Neuroblastoma Cells. literature abstract metadata
- T2 Metabolomics study to reveal cognitive improvement with treatment of Scrophularia buergeriana. literature abstract metadata
- T2 Estrogen-like Activity of Scrophularia buergeriana Root Extracts in MCF-7 Cells. literature abstract metadata