Stephania pierrei
Stephania pierrei
Stephania pierrei 是一种传统上没有特定药用用途的植物。科学研究表明，其块根中含有的氧化科巴宁是一种具有抗炎作用并能通过抑制小鼠多个炎症途径保护急性肺损伤的生物碱。此外，从 Stephania pierrei 中分离出了八种新的生物碱，其中一些显示出比 galanthamine 更强的胆碱酯酶抑制活性。植物的愈伤组织可以产生如 cepharatine、tetrandrine 和 fangchinoline 等次级代谢物，表明其可持续生产天然产物的潜力。证据表明，氧化科巴宁通过调节巨噬细胞中的多个信号通路显著下调炎症反应。尚未记录重大安全问题或药物相互作用，但需要进一步研究以全面了解其应用和效果。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从Stephania pierrei块根中提取的氧化克雷班因可减轻小鼠由LPS诱导的急性肺损伤并抑制多种炎症途径。
- 从 Stephania pierrei 中分离出了八种新的生物碱，其中一些显示出比 galanthamine 更强的胆碱酯酶抑制活性。
- 研究发现，Stephania pierrei 的愈伤组织可以产生包括 cepharantine、tetrandrine 和 fangchinoline 在内的次生代谢物，具有可持续植物化学生产潜力。
- 从Stephania pierrei块茎中提取的氧化克雷班因显著抑制了由多种信号通路在巨噬细胞中下调引起的炎症反应。
Frequently asked questions
What is Stephania pierrei?
Stephania pierrei (Stephania pierrei) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stephania pierrei?
4 sourced findings are recorded for Stephania pierrei; the strongest carries evidence grade D. For example: 从Stephania pierrei块根中提取的氧化克雷班因可减轻小鼠由LPS诱导的急性肺损伤并抑制多种炎症途径。
How strong is the evidence for Stephania pierrei?
The strongest finding for Stephania pierrei carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania pierrei safe? What are the side effects?
No major safety issues are recorded for Stephania pierrei in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania pierrei interact with medications?
No drug interactions are recorded for Stephania pierrei in our sources. This does not rule them out — check with a pharmacist.
Is Stephania pierrei a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Stephapierrines A-H, new tetrahydroprotoberberine and aporphine alkaloids from the tubers of Stephania pierrei Diels and their anti-cholinesterase activities. literature abstract metadata
- T2 Oxocrebanine from Stephania pierrei exerts macrophage anti-inflammatory effects by downregulating the NF-κB, MAPK, and PI3K/Akt signalling pathways. literature abstract metadata
- T2 Protective effects of Stephania pierrei tuber-derived oxocrebanine against LPS-induced acute lung injury in mice. literature abstract metadata
- T2 In vitro propagation of Stephania pierrei diels and exploration of its potential as sustainable phytochemical production from tuber and callus. literature abstract metadata