Stephania venosa
Stephania venosa
Stephania venosa，这种植物在某些传统草药实践中被传统上使用，但没有记录特定的传统用途。科学研究表明，来自 Stephania venosa 的 crebanine 可以显著抑制 RCC 肿瘤并导致 G1 细胞周期停滞，从而抑制细胞增殖和细胞死亡。此外，crebanine（CN）和 O-甲基丁香碱（OMBC）通过抑制 Akt/NF-κB 信号通路增强了 SKOV3 卵巢癌细胞对顺铂的敏感性。这些发现表明其可能具有抗癌作用，特别是针对肝细胞癌和卵巢癌。虽然没有记录到重大安全问题或药物相互作用，但目前的科学证据有限，需要更多研究来全面了解其疗效和应用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 克雷班因显著抑制了肾细胞癌的克隆，并诱导G1期阻滞和亚G1积累，导致增殖和凋亡被抑制。
- 来自 Stephania venosa 的克雷班宁通过调节 EZH2/DUSP1/Akt 信号通路抑制肝细胞癌的增殖和侵袭。
- OMP 和 DC 抑制了由 LPS 引起的 RAW264.7 巨噬细胞炎症反应，通过抑制 NF-κB 和 AP-1 活化。
- CN 和 OMBC 通过抑制Akt/NF-κB 信号通路增强 SKOV3 卵巢癌细胞对顺铂的敏感性。
Frequently asked questions
What is Stephania venosa?
Stephania venosa (Stephania venosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stephania venosa?
4 sourced findings are recorded for Stephania venosa; the strongest carries evidence grade D. For example: 克雷班因显著抑制了肾细胞癌的克隆，并诱导G1期阻滞和亚G1积累，导致增殖和凋亡被抑制。
How strong is the evidence for Stephania venosa?
The strongest finding for Stephania venosa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania venosa safe? What are the side effects?
No major safety issues are recorded for Stephania venosa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania venosa interact with medications?
No drug interactions are recorded for Stephania venosa in our sources. This does not rule them out — check with a pharmacist.
Is Stephania venosa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Alkaloids from Stephania venosa as Chemo-Sensitizers in SKOV3 Ovarian Cancer Cells via Akt/NF-κB Signaling. literature abstract metadata
- T2 O-Methylbulbocapnine and Dicentrine Suppress LPS-Induced Inflammatory Response by Blocking NF-κB and AP-1 Activation through Inhibiting MAPKs and Akt Signaling in RAW264.7 Macrophages. literature abstract metadata
- T2 Crebanine Induces Cell Death and Alters the Mitotic Process in Renal Cell Carcinoma In Vitro. literature abstract metadata
- T2 EZH2/DUSP1/Akt signaling axis mediates the inhibitory effect of crebanine on hepatocellular carcinoma progression. literature abstract metadata