Stephania venosa
Stephania venosa
Stephania venosa，一种传统上在某些草药实践中使用的植物但没有特定的传统用途记录，因其潜在的医疗特性而引起了注意。科学研究表明，来自 Stephania venosa 的 crebanine 可以显著抑制肾细胞癌的生长并诱导 G1 期阻滞，从而抑制增殖和凋亡。此外，它还被发现通过调节 EZH2/DUSP1/Akt 信号通路来抑制肝细胞癌的生长和侵袭。其他化合物如 OMP 和 DC 在 LPS 引发的炎症反应中通过抑制 NF-κB 和 AP-1 激活在 RAW264.7 巨噬细胞中表现出抗炎作用。CN 和 OMBC 可以通过抑制 Akt/NF-κβ 信号通路增加 SKOV3 卵巢癌细胞对顺铂的敏感性，表明与化疗可能存在协同效应。迄今为止，Stephania venosa 没有记录到重大安全问题或药物相互作用，但进一步的研究是必要的，以便全面了解其治疗应用和潜在风险。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 克雷班因显著抑制了肾细胞癌的克隆，并诱导G1期阻滞和亚G1积累，导致增殖和凋亡被抑制。
- 来自 Stephania venosa 的克雷班宁通过调节 EZH2/DUSP1/Akt 信号通路抑制肝细胞癌的增殖和侵袭。
- OMP 和 DC 抑制了由 LPS 引起的 RAW264.7 巨噬细胞炎症反应，通过抑制 NF-κB 和 AP-1 活化。
- CN 和 OMBC 通过抑制Akt/NF-κB 信号通路增强 SKOV3 卵巢癌细胞对顺铂的敏感性。
Frequently asked questions
What is Stephania venosa?
Stephania venosa (Stephania venosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stephania venosa?
4 sourced findings are recorded for Stephania venosa; the strongest carries evidence grade D. For example: 克雷班因显著抑制了肾细胞癌的克隆，并诱导G1期阻滞和亚G1积累，导致增殖和凋亡被抑制。
How strong is the evidence for Stephania venosa?
The strongest finding for Stephania venosa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stephania venosa safe? What are the side effects?
No major safety issues are recorded for Stephania venosa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stephania venosa interact with medications?
No drug interactions are recorded for Stephania venosa in our sources. This does not rule them out — check with a pharmacist.
Is Stephania venosa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Alkaloids from Stephania venosa as Chemo-Sensitizers in SKOV3 Ovarian Cancer Cells via Akt/NF-κB Signaling. literature abstract metadata
- T2 O-Methylbulbocapnine and Dicentrine Suppress LPS-Induced Inflammatory Response by Blocking NF-κB and AP-1 Activation through Inhibiting MAPKs and Akt Signaling in RAW264.7 Macrophages. literature abstract metadata
- T2 Crebanine Induces Cell Death and Alters the Mitotic Process in Renal Cell Carcinoma In Vitro. literature abstract metadata
- T2 EZH2/DUSP1/Akt signaling axis mediates the inhibitory effect of crebanine on hepatocellular carcinoma progression. literature abstract metadata