stephania-root
Stephania tetrandra
Stephania tetrandra 是一种传统中药植物，用于多种草药配方。尽管其具体的传统用途尚未详细记录，但它已被探索以在不同医学传统中寻找潜在的治疗益处。科学研究表明，来自 Stephania tetrandra 的 fangchinoline 可诱导循环肿瘤细胞衰老，可能减少小鼠模型中的转移而无明显毒性。此外，该植物中的 tetrandrine 在缺氧条件下显示出心肌细胞存活率提高和乳酸脱氢酶释放减少，与其他生物碱相比更为优异。tetrandrine 还通过依赖性和非依赖性自噬机制调节自噬并降低 SARS-CoV-2 在肺上皮细胞中的复制。从安全性来看，没有记录到重大问题，并且目前尚未报告与 Stephania tetrandra 相关的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自小通草的芳岑宁可引起循环肿瘤细胞衰老，减少小鼠模型中的转移且无明显毒性。
- 该研究通过网络药理学和分子对接，确定了小通草在治疗顺铂耐药性卵巢癌中的潜在靶点和机制。
- 从tetrandrine（来源于Stephania tetrandra）在缺氧/再氧条件下改善了心肌细胞的存活率并减少了LDH释放，表明其可能具有保护心脏免受损伤的潜力。
- tetrandrine 调节自噬并减少肺上皮细胞中 SARS-CoV-2 的复制，涉及依赖性和非依赖性机制。
Frequently asked questions
What is stephania-root?
stephania-root (Stephania tetrandra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about stephania-root?
4 sourced findings are recorded for stephania-root; the strongest carries evidence grade D. For example: 来自小通草的芳岑宁可引起循环肿瘤细胞衰老，减少小鼠模型中的转移且无明显毒性。
How strong is the evidence for stephania-root?
The strongest finding for stephania-root carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is stephania-root safe? What are the side effects?
No major safety issues are recorded for stephania-root in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does stephania-root interact with medications?
No drug interactions are recorded for stephania-root in our sources. This does not rule them out — check with a pharmacist.
What are the common names of stephania-root?
stephania-root is also known as: Стефания четырёхтычинковая.
Is stephania-root a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Exploring the mechanism of Stephania tetrandra S. Moore in the treatment of cisplatin resistance against ovarian cancer through integration of network pharmacology and molecular docking. literature abstract metadata
- T2 Fangchinoline suppresses melanoma metastasis by inducing senescence of circulating tumor cells. literature abstract metadata
- T2 The protective effects of alkaloids from Stephania tetrandra S. Moore on H9C2 cardiomyocytes. literature abstract metadata
- T2 Tetrandrine-driven autophagy suppresses SARS-CoV-2 replication by modulating cholesterol and IGF signaling pathways. literature abstract metadata