Uncaria sinensis
Uncaria sinensis
Uncaria sinensis，也称为Gouteng或Uncaria，是一种传统的中国草药植物。其在民间和草本传统中的主要用途是治疗各种疾病，如风湿、高血压和精神障碍；然而，具体的传统用途尚未得到充分记录。科学研究已经识别出潜在的肝毒性成分，如cadambine、rhynchophylline、corynoxeine、isocorynoxeine、strictosamide和mitraphylline，这些成分可能影响IL-17信号通路，但证据仍然有限。此外，代谢组学策略有效地区分了五种Uncaria物种，有助于其鉴定。从Uncaria sinensis制备的Jodeungsan在细胞模型中显示出神经保护和抗神经炎症作用；然而，单个化合物的具体贡献尚不明确。Uncaria sinensis的水提取物抑制RANKL诱导的破骨细胞分化和骨吸收而不影响破骨细胞存活，表明对骨骼健康的潜在益处。迄今为止尚未记录到重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Jodeungsan 在细胞模型中通过其成分显示了神经保护和抗神经炎症作用，但未提供具体剂量。
- 研究发现， Uncaria sinensis 具有多种药理作用，包括神经保护、抗氧化、抗炎、抗癌和抗菌作用，但并未提供具体健康结果。
- 研究在 Uncariae Ramulus Cum Uncis 中鉴定出了潜在的肝毒性成分（卡达宾、逆布林碱、科罗诺辛、异科罗诺辛、石松素和麻黄碱），这些成分可能会影响 IL-17 信号通路。
- 代谢组学策略有效地区分了五种 Uncaria 种类，有助于其鉴定。
- Uncaria sinensis 的水提取物抑制RANKL诱导的破骨细胞分化和骨吸收而不影响破骨细胞存活。
Frequently asked questions
What is Uncaria sinensis?
Uncaria sinensis (Uncaria sinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Uncaria sinensis?
5 sourced findings are recorded for Uncaria sinensis; the strongest carries evidence grade D. For example: Jodeungsan 在细胞模型中通过其成分显示了神经保护和抗神经炎症作用，但未提供具体剂量。
How strong is the evidence for Uncaria sinensis?
The strongest finding for Uncaria sinensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Uncaria sinensis safe? What are the side effects?
No major safety issues are recorded for Uncaria sinensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Uncaria sinensis interact with medications?
No drug interactions are recorded for Uncaria sinensis in our sources. This does not rule them out — check with a pharmacist.
Is Uncaria sinensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Water extract of Uncaria sinensis suppresses RANKL-induced bone loss by attenuating osteoclast differentiation and bone resorption. literature abstract metadata
- T2 Quantitative Analysis and Biological Efficacies regarding the Neuroprotective and Antineuroinflammatory Actions of the Herbal Formula Jodeungsan in HT22 Hippocampal Cells and BV-2 Microglia. literature abstract metadata
- T2 A metabolomics strategy for authentication of plant medicines with multiple botanical origins, a case study of Uncariae Rammulus Cum Uncis. literature abstract metadata
- T2 Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on "component-target-pathway" network. literature abstract metadata
- T2 Advanced researches of traditional uses, phytochemistry, pharmacology, and toxicology of medical Uncariae Ramulus Cum Uncis. literature abstract metadata