Cat's Claw
Uncaria tomentosa
Uncaria tomentosa，又称猫爪，起源于南美洲的传统医学实践。它传统上用于治疗各种疾病，包括关节炎和消化系统紊乱，但不同土著文化的具体用途有所不同。关于 Uncaria tomentosa 的科学证据有限，但它显示出潜在的好处。例如，Imoviral® 补充剂在某些研究中导致 TNF-α 和 IL-1β 早期短暂上调，表明免疫系统的调节作用。此外，Rhy 在高脂饮食喂养的兔子中通过抑制氧化 LDL 吸收和减少炎症反应减缓了主动脉斑块进展并改善了血管组织学。Uncaria tomentosa 的提取物也显示出对某些癌细胞系的选择性细胞毒性，最令人鼓舞的结果来自粗水提取物树皮和富含五环氧吲哚生物碱的提取物。奎宁酸进一步增强了这一效果，通过调节 Ras/MAPK 信号通路并增加 KHYG-1 细胞中干扰素-γ 的表达来增强其作用。安全性数据显示没有重大问题，但需要进行更全面的长期研究以完全评估潜在风险。目前尚未报告 Uncaria tomentosa 与药物之间的相互作用，尽管鉴于其多种生物活性，进一步的研究仍然必要。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Imoviral® 补充剂导致早期短暂的TNF-α和IL-1β上调，与其他免疫基因相比，其他组别中的变化有限。
- Rhy 减少了主动脉斑块的进展，并通过抑制氧化低密度脂蛋白（ox-LDL）摄取和减少炎症反应改善了高脂饮食喂养兔的血管组织学。
- 从 Uncaria tomentosa 提取物显示出对某些癌细胞系的选择性细胞毒性，其中粗水提取物和富含五环氧化吲哚生物碱的提取物最具前景。
- 奎尼酸增强了KHYG-1细胞的细胞毒性，通过调节Ras/MAPK信号传导途径并增加干扰素-γ的表达。
Frequently asked questions
What is Cat's Claw?
Cat's Claw (Uncaria tomentosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cat's Claw?
4 sourced findings are recorded for Cat's Claw; the strongest carries evidence grade A. For example: Imoviral® 补充剂导致早期短暂的TNF-α和IL-1β上调，与其他免疫基因相比，其他组别中的变化有限。
How strong is the evidence for Cat's Claw?
The strongest finding for Cat's Claw carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Cat's Claw safe? What are the side effects?
No major safety issues are recorded for Cat's Claw in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cat's Claw interact with medications?
No drug interactions are recorded for Cat's Claw in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cat's Claw?
Cat's Claw is also known as: Ункария опушённая, Liane du Pérou.
Is Cat's Claw a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Cytotoxic effect of different Uncaria tomentosa (cat's claw) extracts, fractions on normal and cancer cells: a systematic review. literature abstract metadata
- T2 Rhynchophylline alleviates early atherosclerosis by attenuating oxidized low-density lipoprotein-induced foam cell formation and endothelial dysfunction. literature abstract metadata
- T2 Quinovic Acid Enhances the Cytotoxicity of KHYG-1 Cells by Modulating the Ras/MAPK Signalling Pathway and Interferon-Gamma Expression. literature abstract metadata
- T2 Evaluation of Imoviral® effects on early immune response in Sparus aurata challenged with Vibrio anguillarum. literature abstract metadata