Gambier
Uncaria gambir
Uncaria gambir 是一种传统上在东南亚医学中使用的植物，特别是在马来西亚和印度尼西亚。尽管其具体的传统用途尚未详细记录，但科学证据表明，Uncaria gambir 的乙酸乙酯提取物（Epi-A）表现出强大的抗疟疾活性，并且在体外和体内均未显示出显著的毒性。研究发现，strictosamide 和 3α-dihydrocadambine 是活性成分，分别显示了明显的磷酸酶抑制作用和血管扩张效应。此外，在100 mg/L 和 200 mg/L 的剂量下，提取物增强了 SOD 和 CAT 酶的活性，并且在 200 mg/L 剂量下将肝细胞死亡率降低了 17.97%。另一项研究中，补充 1% Gambier 将甲烷排放减少了 33.43%，与对照组相比。迄今为止，尚未记录 Uncaria gambir 的主要安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Epi-A在体外和体内均表现出强大的抗疟疾活性且无明显毒性。
- 研究在乌尼卡尔·甘比尔（Uncaria gambir）中鉴定了strictosamide和3α-二氢香豆宁，分别显示出对CDC25B磷酸酶的显著抑制作用和舒张血管活性。
- 100 mg/L 和 200 mg/L 的乌梅乙酸提取物剂量增强了 SOD 和 CAT 酶的活性，其中 200 mg/L 剂量减少了肝细胞死亡率 17.97%。
- 补充1%羊角豆可将甲烷排放量减少33.43%，与对照组相比。
Frequently asked questions
What is Gambier?
Gambier (Uncaria gambir) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gambier?
4 sourced findings are recorded for Gambier; the strongest carries evidence grade D. For example: Epi-A在体外和体内均表现出强大的抗疟疾活性且无明显毒性。
How strong is the evidence for Gambier?
The strongest finding for Gambier carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gambier safe? What are the side effects?
No major safety issues are recorded for Gambier in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gambier interact with medications?
No drug interactions are recorded for Gambier in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gambier?
Gambier is also known as: Гамбир.
Is Gambier a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Comparative effects of Gamal (Gliricidia sepium)-based diets supplemented with Gambier (Uncaria gambir) or direct-fed microbials on rumen fermentation, nutrient digestibility, microbial protein synthesis, and methane mitigation in beef catt literature abstract metadata
- T2 Metabolomic study and valuation of ethyl acetate extract of Uncaria gambir (W. Hunter) Roxb. as a natural antioxidant against lead acetate-induced free radicals. literature abstract metadata
- T2 Chemical components from Uncaria gambir (W.Hunter) Roxb. and their preliminary bioactivities in CDC25B phosphatase inhibition and vasodilatory activity. literature abstract metadata
- T2 Exploring the antimalarial potential of (+)-2,2'-epicytoskyrin A: in vitro and in vivo studies of a bioactive metabolite from endophytic fungus Diaporthe sp. GNBP-10. literature abstract metadata