Chinese Chaste Tree
Vitex negundo
Vitex negundo，这种植物传统上在各种民间医疗实践中被使用，但没有特定的文献记录的传统用途。它在多种药理活性中显示出潜力。研究表明其可能具有抗炎和抗氧化作用以及肝保护特性；然而，由于研究设计的差异性，证据尚不充分。一项研究发现，Vitex negundo 根提取物和 Allium cepa 蒜头甲醇提取物均能显著提供抗氧化活性，并减轻由替诺福韦引起的肾毒性在大鼠中。此外，在 Vitex negundo 的种子中鉴定出了十七种生物活性的植物成分，显示出潜在的抗菌作用。叶片提取物还通过调节 TLR-4/NF-κB p65/iNOS 途径对 LPS 引起的急性肺损伤具有保护作用。尚未记录该植物的重大安全问题或药物相互作用报告，但需要进一步研究以全面了解其治疗潜力和安全性概况。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Vitex negundo 展示了多种药理活性，包括抗炎、抗氧化和肝保护作用，但研究设计中的不一致性限制了最终结论。
- 大蒜鳞茎的甲醇提取物和接骨木根的水醇提物显示出显著的抗氧化活性，并减轻了替诺福韦诱导的肾脏毒性在大鼠模型中的表现。
- 从 Vitex negundo 叶提取物通过减少炎症和调节 TLR-4/NF-κB p65/iNOS 路径减轻了由 LPS 引起的小鼠急性肺损伤。
- 研究在接骨木果中鉴定了十七种生物活性植物成分，显示出潜在的抗菌活性。
Frequently asked questions
What is Chinese Chaste Tree?
Chinese Chaste Tree (Vitex negundo) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese Chaste Tree?
4 sourced findings are recorded for Chinese Chaste Tree; the strongest carries evidence grade A. For example: Vitex negundo 展示了多种药理活性，包括抗炎、抗氧化和肝保护作用，但研究设计中的不一致性限制了最终结论。
How strong is the evidence for Chinese Chaste Tree?
The strongest finding for Chinese Chaste Tree carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese Chaste Tree safe? What are the side effects?
No major safety issues are recorded for Chinese Chaste Tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese Chaste Tree interact with medications?
No drug interactions are recorded for Chinese Chaste Tree in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese Chaste Tree?
Chinese Chaste Tree is also known as: Muguet bleu.
Is Chinese Chaste Tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Vitex negundo Linn.: A decade of advances in phytochemistry, pharmacological activities, and biotechnological interventions (2015-2025) - A comprehensive review. literature abstract metadata
- T2 Phytochemical profiling of Vitex negundo seeds via UHPLC-QTOF-MS/MS analyses with antimicrobial evaluation and in silico targeting of DNA Gyrase B and Secreted Aspartic Proteinase 2 (SAP2). literature abstract metadata
- T2 Unravelling the potential of Vitex negundo leaf extract in LPS-induced acute lung injury in mice through modulation of the TLR-4/NF-κB p65/iNOS pathway: Insights from integrated phytochemical characterization, in silico, and in vivo analysi literature abstract metadata
- T2 Xanthine oxidase inhibition by medicinal plants mitigates tenofovir-induced nephrotoxicity: a comprehensive computational and experimental study. literature abstract metadata