Dragon's Head
Dracocephalum
Dracocephalum, a genus of plants native to Europe and Asia, has traditionally been used sparingly or not at all in herbal medicine. Scientific evidence indicates that extracts from Dracocephalum botryoides exhibit promising antioxidant, antimicrobial, and antibiofilm activities with minimal toxicity against skin cells. Additionally, the use of Dracocephalum in offspring of stressed parents showed significant reductions in seizure frequency and duration, as well as prolonged latency to onset. In another study, combining phenylalanine with A. niger extract enhanced total phenolic and flavonoid accumulation in D. kotschyi hairy roots. Tiliacorin from Dracocephalum moldavica demonstrated potential antipsychotic effects by restoring PDE10A/cAMP/PKA/CREB signaling pathways, though more research is needed to confirm these findings. No major safety concerns or drug interactions have been recorded for this genus of plants.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Das Essigewässer von Dracocephalum botryoides zeigte beachtliche antioxidantische, antimikrobielle und antibiopelzige Aktivitäten mit geringer Zytotoxizität gegenüber den HaCaT-Zellen.
- Die kombinierte Anwendung von 10 mM Phenylalanin und 1,5 mg/L A. niger-Extrakt maximierte die Gesamtakkumulation von Phenolen und Flavonoide in den haarigen Wurzeln von D. kotschyi.
- Die Behandlung mit einem DM-Extrakt während der Gametogenese verringerte die Häufigkeit und Dauer der Krämpfe bei den Nachkommen von gestressten Ratten ohne Einfluss auf ihr Körpergewichtszuwachs.
- Tilia aus Dracocephalum moldavica zeigte Potenzial als Antipsychotikum, indem sie die PDE10A/cAMP/PKA/CREB-Signale in einer Mäuse-Modell für Schizophrenie wiederherstellte.
- Der Gattung Dracocephalum zählen Polyphenole wie Flavone und Phenolsäuren an, wobei einige Arten in etnomedizinischen Systemen traditionell verwendet werden.
- Die Wirkungen von Aluminiumoxid-Nanopartikeln (Al2O3NPs) auf Dracocephalum kotschyi Boiss hingen von der Dosis ab, wobei ein Anstieg bei 50 ppm und eine Hemmung bei 1000 ppm beobachtet wurde.
Frequently asked questions
What is Dragon's Head?
Dragon's Head (Dracocephalum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dragon's Head?
6 sourced findings are recorded for Dragon's Head; the strongest carries evidence grade D. For example: Das Essigewässer von Dracocephalum botryoides zeigte beachtliche antioxidantische, antimikrobielle und antibiopelzige Aktivitäten mit geringer Zytotoxizität gegenüber den HaCaT-Zellen.
How strong is the evidence for Dragon's Head?
The strongest finding for Dragon's Head carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dragon's Head safe? What are the side effects?
No major safety issues are recorded for Dragon's Head in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dragon's Head interact with medications?
No drug interactions are recorded for Dragon's Head in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dragon's Head?
Dragon's Head is also known as: Змееголовник, Dracocéphale.
Is Dragon's Head a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Synergistic effects of Aspergillus niger ATCC 13794 and phenylalanine precursor feeding on enhancing phenolic compound biosynthesis in Dracocephalum kotschyi boiss: hairy roots culture. literature abstract metadata
- T2 The bilateral effects of Al2O3NPs on Dracocephalum kotschyi Boiss: Insights from physiological responses, antioxidant defense efficacy, and phytochemical yield. literature abstract metadata
- T2 Chemical Composition, Antimicrobial, Antibiofilm Activities, and Cytotoxicity of the Essential Oil of Dracocephalum botryoides Stev. literature abstract metadata
- T2 Effects of Pregestational Stress and Concomitant Administration of Dracocephalum moldavica Extract on Seizure Behaviours in Next Generation Developing Rats. literature abstract metadata
- T2 Phytochemical Composition and Biological Activities of Dracocephalum Species Native to Kazakhstan: A Comprehensive Review. literature abstract metadata
- T2 Integrated network pharmacology and UHPLC-Q-TOF LC-MS/MS phytochemical profiling demonstrate tilianin-mediated restoration of PDE10A/cAMP/PKA/CREB signaling in an MK-801-induced schizophrenia-like model. literature abstract metadata