Dragon's Head

Dracocephalum

Dracocephalum, a genus of plants native to Europe and Asia, has traditionally been used sparingly or not at all in herbal medicine. Scientific evidence indicates that extracts from Dracocephalum botryoides exhibit promising antioxidant, antimicrobial, and antibiofilm activities with minimal toxicity against skin cells. Additionally, the use of Dracocephalum in offspring of stressed parents showed significant reductions in seizure frequency and duration, as well as prolonged latency to onset. In another study, combining phenylalanine with A. niger extract enhanced total phenolic and flavonoid accumulation in D. kotschyi hairy roots. Tiliacorin from Dracocephalum moldavica demonstrated potential antipsychotic effects by restoring PDE10A/cAMP/PKA/CREB signaling pathways, though more research is needed to confirm these findings. No major safety concerns or drug interactions have been recorded for this genus of plants.

De un vistazo
Mejor evidencia
D
Precauciones

Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.

Lo que dice la ciencia

  • El aceite esencial de Dracocephalum botryoides mostró actividades antioxidantes, antimicrobianas y antibiopelículas notables con baja citototoxicidad en las células HaCaT. D PMID
  • La aplicación combinada de 10 mM fenilalanina y 1,5 mg/L de extracción de A. niger maximizó la acumulación total de fitoquímicos polifenoles y flavonoides en las raíces peladas de D. kotschyi. D PMID
  • El tratamiento con extracto de DM durante la gametogénesis redujo la frecuencia y duración de los episodios convulsivos en los descendientes de ratas estresadas sin afectar su ganancia de peso corporal. D PMID
  • Tilia de Dracocephalum moldavica mostró potencial como antipsicótico restaurando la señalización PDE10A/cAMP/PKA/CREB en un modelo de esquizofrenia en ratones. D PMID
  • El género Dracocephalum contiene polifenoles que incluyen flavonoides y ácidos fenólicos, con algunas especies utilizadas tradicionalmente en sistemas etnomédicos. D PMID
  • Los efectos de las nanopartículas de óxido de aluminio (Al2O3NPs) en Dracocephalum kotschyi Boiss variaron según la dosis, promoviendo el crecimiento a 50 ppm mientras que lo inhibían a 1000 ppm. D PMID

Frequently asked questions

What is Dragon's Head?

Dragon's Head (Dracocephalum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Dragon's Head?

6 sourced findings are recorded for Dragon's Head; the strongest carries evidence grade D. For example: El aceite esencial de Dracocephalum botryoides mostró actividades antioxidantes, antimicrobianas y antibiopelículas notables con baja citototoxicidad en las células HaCaT.

How strong is the evidence for Dragon's Head?

The strongest finding for Dragon's Head carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Dragon's Head safe? What are the side effects?

No major safety issues are recorded for Dragon's Head in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Dragon's Head interact with medications?

No drug interactions are recorded for Dragon's Head in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Dragon's Head?

Dragon's Head is also known as: Змееголовник, Dracocéphale.

Is Dragon's Head a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Fuentes

  1. T2 Synergistic effects of Aspergillus niger ATCC 13794 and phenylalanine precursor feeding on enhancing phenolic compound biosynthesis in Dracocephalum kotschyi boiss: hairy roots culture. literature abstract metadata
  2. T2 The bilateral effects of Al2O3NPs on Dracocephalum kotschyi Boiss: Insights from physiological responses, antioxidant defense efficacy, and phytochemical yield. literature abstract metadata
  3. T2 Chemical Composition, Antimicrobial, Antibiofilm Activities, and Cytotoxicity of the Essential Oil of Dracocephalum botryoides Stev. literature abstract metadata
  4. T2 Effects of Pregestational Stress and Concomitant Administration of Dracocephalum moldavica Extract on Seizure Behaviours in Next Generation Developing Rats. literature abstract metadata
  5. T2 Phytochemical Composition and Biological Activities of Dracocephalum Species Native to Kazakhstan: A Comprehensive Review. literature abstract metadata
  6. T2 Integrated network pharmacology and UHPLC-Q-TOF LC-MS/MS phytochemical profiling demonstrate tilianin-mediated restoration of PDE10A/cAMP/PKA/CREB signaling in an MK-801-induced schizophrenia-like model. literature abstract metadata