Dracocéphale
Dracocephalum · Dragon's Head
Dracocephalum, a genus of plants native to Europe and Asia, has traditionally been used sparingly or not at all in herbal medicine. Scientific evidence indicates that extracts from Dracocephalum botryoides exhibit promising antioxidant, antimicrobial, and antibiofilm activities with minimal toxicity against skin cells. Additionally, the use of Dracocephalum in offspring of stressed parents showed significant reductions in seizure frequency and duration, as well as prolonged latency to onset. In another study, combining phenylalanine with A. niger extract enhanced total phenolic and flavonoid accumulation in D. kotschyi hairy roots. Tiliacorin from Dracocephalum moldavica demonstrated potential antipsychotic effects by restoring PDE10A/cAMP/PKA/CREB signaling pathways, though more research is needed to confirm these findings. No major safety concerns or drug interactions have been recorded for this genus of plants.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'huile essentielle de Dracocephalum botryoides a montré des activités antioxydantes, antimicrobiennes et antibiofilm notables avec une faible cytotoxicité sur les cellules HaCaT.
- L'application combinée de 10 mM de phénylalanine et de 1,5 mg/L d'extrait de A. niger a maximisé l'accumulation totale de polyphénols et de flavonoïdes chez les racines pelées de D. kotschyi.
- Le traitement par un extrait de DM pendant la gamétogenèse a réduit la fréquence et la durée des crises chez les descendants de rats stressés sans affecter leur gain de poids corporel.
- La tilleul provenant de Dracocephalum moldavica a montré du potentiel comme antipsychotique en rétablissant le signalisation PDE10A/cAMP/PKA/CREB dans un modèle de schizophrénie chez la souris.
- Le genre Dracocephalum contient des polyphénols comprenant des flavonoïdes et des acides phénoliques, avec certaines espèces utilisées traditionnellement dans les systèmes ethnomédicinaux.
- Les effets des nanoparticules d'oxyde d'aluminium (Al2O3NPs) sur Dracocephalum kotschyi Boiss variaient en fonction de la dose, favorisant le croissance à 50 ppm tout en l'inhibant à 1000 ppm.
Frequently asked questions
What is Dracocéphale?
Dracocéphale (Dracocephalum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dracocéphale?
6 sourced findings are recorded for Dracocéphale; the strongest carries evidence grade D. For example: L'huile essentielle de Dracocephalum botryoides a montré des activités antioxydantes, antimicrobiennes et antibiofilm notables avec une faible cytotoxicité sur les cellules HaCaT.
How strong is the evidence for Dracocéphale?
The strongest finding for Dracocéphale carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dracocéphale safe? What are the side effects?
No major safety issues are recorded for Dracocéphale in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dracocéphale interact with medications?
No drug interactions are recorded for Dracocéphale in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dracocéphale?
Dracocéphale is also known as: Dragon's Head, Змееголовник.
Is Dracocéphale a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Synergistic effects of Aspergillus niger ATCC 13794 and phenylalanine precursor feeding on enhancing phenolic compound biosynthesis in Dracocephalum kotschyi boiss: hairy roots culture. literature abstract metadata
- T2 The bilateral effects of Al2O3NPs on Dracocephalum kotschyi Boiss: Insights from physiological responses, antioxidant defense efficacy, and phytochemical yield. literature abstract metadata
- T2 Chemical Composition, Antimicrobial, Antibiofilm Activities, and Cytotoxicity of the Essential Oil of Dracocephalum botryoides Stev. literature abstract metadata
- T2 Effects of Pregestational Stress and Concomitant Administration of Dracocephalum moldavica Extract on Seizure Behaviours in Next Generation Developing Rats. literature abstract metadata
- T2 Phytochemical Composition and Biological Activities of Dracocephalum Species Native to Kazakhstan: A Comprehensive Review. literature abstract metadata
- T2 Integrated network pharmacology and UHPLC-Q-TOF LC-MS/MS phytochemical profiling demonstrate tilianin-mediated restoration of PDE10A/cAMP/PKA/CREB signaling in an MK-801-induced schizophrenia-like model. literature abstract metadata