Kothala himbutu
Salacia reticulata
Salacia reticulata, a plant traditionally used in Ayurvedic medicine, has not been extensively documented for specific traditional uses. Scientific evidence suggests that Salacia reticulata extract may modestly reduce total body fat mass but does not significantly alter body fat percentage compared to placebo. Green-synthesized CuO nanoparticles from the plant caused developmental anomalies and increased mortality in zebrafish embryos at a high concentration, indicating potential toxicity concerns. In type 2 diabetes (T2DM) rats, Salacia reticulata improved insulin sensitivity and glucose homeostasis by enhancing insulin signaling and GLP-1 levels, while a polyherbal formulation containing it showed improvements in glycemic parameters and quality of life without adverse events in T2DM patients; however, further research is needed. No major safety issues or drug interactions have been recorded for Salacia reticulata.
- Beste Evidenz
- B
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Der Extrakt von Salacia reticulata zeigte eine geringe Reduzierung der Gesamtfettmasse, aber es gab keinen signifikanten Unterschied im Fettanteil des Körpers im Vergleich zum Plazebo.
- Grüne-synthetisierte CuO-Nanopartikel aus Salacia reticulata verursachten Entwicklungsanomalien und erhöhten die Sterblichkeitsrate bei Zebrafisch-Embryonen bei einer Konzentration von 200 µL/mL.
- Die polyherbizte Formulation LG hat die glycämischen Parameter und das Lebensqualitätsindex bei Patienten mit Typ-2-Diabetes signifikant verbessert, ohne Nebenwirkungen aufzuweisen.
- Salacia reticulata verbesserte die Insulinempfindlichkeit und den Glukosehaushalt bei Ratten mit Typ-2-Diabetes durch eine verstärkte Insulin-Signallierung und erhöhten GLP-1-Werten.
Frequently asked questions
What is Kothala himbutu?
Kothala himbutu (Salacia reticulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kothala himbutu?
4 sourced findings are recorded for Kothala himbutu; the strongest carries evidence grade B. For example: Der Extrakt von Salacia reticulata zeigte eine geringe Reduzierung der Gesamtfettmasse, aber es gab keinen signifikanten Unterschied im Fettanteil des Körpers im Vergleich zum Plazebo.
How strong is the evidence for Kothala himbutu?
The strongest finding for Kothala himbutu carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Kothala himbutu safe? What are the side effects?
No major safety issues are recorded for Kothala himbutu in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kothala himbutu interact with medications?
No drug interactions are recorded for Kothala himbutu in our sources. This does not rule them out — check with a pharmacist.
Is Kothala himbutu a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 A comparative study of in vivo toxicity in zebrafish embryos synthesized CuO nanoparticles characterized from Salacia reticulata. literature abstract metadata
- T2 Efficacy and Safety of an Ayurveda Herbal Formulation in Uncomplicated Type 2 Diabetes mellitus. literature abstract metadata
- T2 Salacia Reticulata Extract Improves Insulin Sensitivity and Glucose Homeostasis by Activating Insulin Signaling and Glucagon-like Peptide-1 Modulation. literature abstract metadata
- T2 A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of Salacia reticulata Extract for Fat-Mass Reduction in Adults with Overweight/Obesity. literature abstract metadata