Kothala himbutu
Salacia reticulata
Salacia reticulata, a plant traditionally used in Ayurvedic medicine, has not been extensively documented for specific traditional uses. Scientific evidence suggests that Salacia reticulata extract may modestly reduce total body fat mass but does not significantly alter body fat percentage compared to placebo. Green-synthesized CuO nanoparticles from the plant caused developmental anomalies and increased mortality in zebrafish embryos at a high concentration, indicating potential toxicity concerns. In type 2 diabetes (T2DM) rats, Salacia reticulata improved insulin sensitivity and glucose homeostasis by enhancing insulin signaling and GLP-1 levels, while a polyherbal formulation containing it showed improvements in glycemic parameters and quality of life without adverse events in T2DM patients; however, further research is needed. No major safety issues or drug interactions have been recorded for Salacia reticulata.
- Meilleure preuve
- B
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait de Salacia reticulata a montré une réduction modérée de la masse graisseuse corporelle totale, mais aucun changement significatif du pourcentage de graisse corporelle n'a été observé par rapport au placebo.
- Des nanoparticules de CuO synthétisées vertement à partir de Salacia reticulata ont provoqué des anomalies au développement et une augmentation du taux de mortalité chez les embryons de poisson zèbre à une concentration de 200 µL/mL.
- La formulation polyherbale LG a significativement amélioré les paramètres glycémiques et la QoL sans événements indésirables chez les patients atteints de diabète de type 2.
- La Salacia reticulata a amélioré la sensibilité à l'insuline et le homeostase du glucose chez les rats diabétiques de type 2 en renforçant la signalisation de l'insuline et les niveaux de GLP-1.
Frequently asked questions
What is Kothala himbutu?
Kothala himbutu (Salacia reticulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kothala himbutu?
4 sourced findings are recorded for Kothala himbutu; the strongest carries evidence grade B. For example: L'extrait de Salacia reticulata a montré une réduction modérée de la masse graisseuse corporelle totale, mais aucun changement significatif du pourcentage de graisse corporelle n'a été observé par rapport au placebo.
How strong is the evidence for Kothala himbutu?
The strongest finding for Kothala himbutu carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Kothala himbutu safe? What are the side effects?
No major safety issues are recorded for Kothala himbutu in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kothala himbutu interact with medications?
No drug interactions are recorded for Kothala himbutu in our sources. This does not rule them out — check with a pharmacist.
Is Kothala himbutu a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A comparative study of in vivo toxicity in zebrafish embryos synthesized CuO nanoparticles characterized from Salacia reticulata. literature abstract metadata
- T2 Efficacy and Safety of an Ayurveda Herbal Formulation in Uncomplicated Type 2 Diabetes mellitus. literature abstract metadata
- T2 Salacia Reticulata Extract Improves Insulin Sensitivity and Glucose Homeostasis by Activating Insulin Signaling and Glucagon-like Peptide-1 Modulation. literature abstract metadata
- T2 A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of Salacia reticulata Extract for Fat-Mass Reduction in Adults with Overweight/Obesity. literature abstract metadata