FolkKB

Kothala himbutu

Salacia reticulata

Salacia reticulata, a plant traditionally used in Ayurvedic medicine, has not been extensively documented for specific traditional uses. Scientific evidence suggests that Salacia reticulata extract may modestly reduce total body fat mass but does not significantly alter body fat percentage compared to placebo. Green-synthesized CuO nanoparticles from the plant caused developmental anomalies and increased mortality in zebrafish embryos at a high concentration, indicating potential toxicity concerns. In type 2 diabetes (T2DM) rats, Salacia reticulata improved insulin sensitivity and glucose homeostasis by enhancing insulin signaling and GLP-1 levels, while a polyherbal formulation containing it showed improvements in glycemic parameters and quality of life without adverse events in T2DM patients; however, further research is needed. No major safety issues or drug interactions have been recorded for Salacia reticulata.

De un vistazo
Mejor evidencia
B
Precauciones
—

Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.

Lo que dice la ciencia

  • El extracto de Salacia reticulata mostró una reducción moderada en la masa grasa corporal total, pero no se observó un cambio significativo en el porcentaje de grasa corporal en comparación con el placebo. D PMID
  • Nanopartículas sintetizadas verdes de CuO a partir de Salacia reticulata causaron anomalías en el desarrollo y un aumento en la mortalidad en los embriones de peces cebra a una concentración de 200 µL/mL. D PMID
  • La formulación polifloral LG显著改善了T2DM患者的血糖参数和生活质量，且未见不良反应。 B PMID
  • Salacia reticulata mejoró la sensibilidad a la insulina y el homeostasis glucosérico en ratas con diabetes tipo 2 al mejorar la señalización de la insulina y los niveles de GLP-1. D PMID

Frequently asked questions

What is Kothala himbutu?

Kothala himbutu (Salacia reticulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Kothala himbutu?

4 sourced findings are recorded for Kothala himbutu; the strongest carries evidence grade B. For example: El extracto de Salacia reticulata mostró una reducción moderada en la masa grasa corporal total, pero no se observó un cambio significativo en el porcentaje de grasa corporal en comparación con el placebo.

How strong is the evidence for Kothala himbutu?

The strongest finding for Kothala himbutu carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Kothala himbutu safe? What are the side effects?

No major safety issues are recorded for Kothala himbutu in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Kothala himbutu interact with medications?

No drug interactions are recorded for Kothala himbutu in our sources. This does not rule them out — check with a pharmacist.

Is Kothala himbutu a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Fuentes

  1. T2 A comparative study of in vivo toxicity in zebrafish embryos synthesized CuO nanoparticles characterized from Salacia reticulata. literature abstract metadata
  2. T2 Efficacy and Safety of an Ayurveda Herbal Formulation in Uncomplicated Type 2 Diabetes mellitus. literature abstract metadata
  3. T2 Salacia Reticulata Extract Improves Insulin Sensitivity and Glucose Homeostasis by Activating Insulin Signaling and Glucagon-like Peptide-1 Modulation. literature abstract metadata
  4. T2 A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of Salacia reticulata Extract for Fat-Mass Reduction in Adults with Overweight/Obesity. literature abstract metadata

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