Kothala himbutu
Salacia reticulata
Salacia reticulata, a plant traditionally used in Ayurvedic medicine, has not been extensively documented for specific traditional uses. Scientific evidence suggests that Salacia reticulata extract may modestly reduce total body fat mass but does not significantly alter body fat percentage compared to placebo. Green-synthesized CuO nanoparticles from the plant caused developmental anomalies and increased mortality in zebrafish embryos at a high concentration, indicating potential toxicity concerns. In type 2 diabetes (T2DM) rats, Salacia reticulata improved insulin sensitivity and glucose homeostasis by enhancing insulin signaling and GLP-1 levels, while a polyherbal formulation containing it showed improvements in glycemic parameters and quality of life without adverse events in T2DM patients; however, further research is needed. No major safety issues or drug interactions have been recorded for Salacia reticulata.
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从中草药Salacia reticulata提取物显示出轻度减少总体脂肪质量，但与安慰剂相比没有观察到体脂百分比有显著变化。
- 从Salacia reticulata绿色合成的CuO纳米颗粒在浓度为200 µL/mL时导致了斑马鱼胚胎发育异常和死亡率增加。
- 多植物复方LG显著改善了T2DM患者的血糖参数和生活质量，且未见不良反应。
- Salacia reticulata 改善了2型糖尿病大鼠的胰岛素敏感性和血糖稳态，通过增强胰岛素信号传导和GLP-1水平。
Frequently asked questions
What is Kothala himbutu?
Kothala himbutu (Salacia reticulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kothala himbutu?
4 sourced findings are recorded for Kothala himbutu; the strongest carries evidence grade B. For example: 从中草药Salacia reticulata提取物显示出轻度减少总体脂肪质量，但与安慰剂相比没有观察到体脂百分比有显著变化。
How strong is the evidence for Kothala himbutu?
The strongest finding for Kothala himbutu carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Kothala himbutu safe? What are the side effects?
No major safety issues are recorded for Kothala himbutu in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kothala himbutu interact with medications?
No drug interactions are recorded for Kothala himbutu in our sources. This does not rule them out — check with a pharmacist.
Is Kothala himbutu a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 A comparative study of in vivo toxicity in zebrafish embryos synthesized CuO nanoparticles characterized from Salacia reticulata. literature abstract metadata
- T2 Efficacy and Safety of an Ayurveda Herbal Formulation in Uncomplicated Type 2 Diabetes mellitus. literature abstract metadata
- T2 Salacia Reticulata Extract Improves Insulin Sensitivity and Glucose Homeostasis by Activating Insulin Signaling and Glucagon-like Peptide-1 Modulation. literature abstract metadata
- T2 A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of Salacia reticulata Extract for Fat-Mass Reduction in Adults with Overweight/Obesity. literature abstract metadata