Clerodendrum glandulosum
Clerodendrum glandulosum
Clerodendrum glandulosum is a plant traditionally used in various remedies across different cultures for treating coughs, rheumatism, and diabetes. In traditional medicine, it is employed to address respiratory issues and joint pain, as well as manage blood sugar levels. Scientific evidence suggests that the ethyl acetate fraction from its leaves has shown significant anti-oxidative properties and mitochondrial protection effects, potentially upregulating PGC1α and TFAM. Additionally, studies indicate that extracts of Clerodendrum glandulosum may have promise in diabetic wound healing and reducing cholesterol levels in atherosclerotic rats; however, the specific efficacy and recommended dosages are not clearly defined. The polyphenol-rich fraction from its leaves has also demonstrated anti-hyperglycemic and antioxidative effects comparable to standard treatments in diabetic animals. No major safety concerns or recorded drug interactions have been noted for Clerodendrum glandulosum, though further research is needed to fully understand its potential benefits and applications.
- Traditionally for
- cough · rheumatism
- Traditions
- traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- cough
- rheumatism
- diabetes
What the science says
- The ethyl acetate fraction from Clerodendrum glandulosum leaves showed significant anti-oxidative and mitochondrial protective effects, upregulating PGC1α and TFAM.
- The study found that Clerodendrum glandulosum extract impregnated silver nanoparticle-loaded chitosan-PEG hydrogel showed promise in diabetic wound healing with improved closure and matrix formation.
- EAF from C. glandulosum reduced serum cholesterol and LDL levels in atherosclerotic rats without detailed dose information provided.
- The polyphenol-rich fraction of Clerodendrum glandulosum leaf extract showed anti-hyperglycemic and antioxidative effects in diabetic rats, comparable to a standard treatment.
Frequently asked questions
What is Clerodendrum glandulosum?
Clerodendrum glandulosum (Clerodendrum glandulosum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Clerodendrum glandulosum traditionally used for?
Traditional sources record Clerodendrum glandulosum for: cough, rheumatism, diabetes. This reflects traditional use, not a proven medical treatment.
Which traditions use Clerodendrum glandulosum?
Clerodendrum glandulosum appears in these traditions in our sources: traditional.
What does the scientific evidence say about Clerodendrum glandulosum?
4 sourced findings are recorded for Clerodendrum glandulosum; the strongest carries evidence grade D. For example: The ethyl acetate fraction from Clerodendrum glandulosum leaves showed significant anti-oxidative and mitochondrial protective effects, upregulating PGC1α and TFAM.
How strong is the evidence for Clerodendrum glandulosum?
The strongest finding for Clerodendrum glandulosum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Clerodendrum glandulosum safe? What are the side effects?
No major safety issues are recorded for Clerodendrum glandulosum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Clerodendrum glandulosum interact with medications?
No drug interactions are recorded for Clerodendrum glandulosum in our sources. This does not rule them out — check with a pharmacist.
Is Clerodendrum glandulosum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Phenolic enriched fraction of Clerodendrum glandulosum Lindl. leaf extract ameliorates hyperglycemia and oxidative stress in streptozotocin-nicotinamide induced diabetic rats. literature abstract metadata
- T2 A novel chitosan-PEG hydrogel embedded with in situ silver nanoparticles of Clerodendrum glandulosum Lindl. extract: evaluation of its in vivo diabetic wound healing properties using an image-guided machine learning model. literature abstract metadata
- T2 Phenylethanoid glycoside-enriched fraction of Clerodendrum glandulosum ameliorates oxidative stress and mitochondrial dysfunction via PGC1α/TFAM upregulation. literature abstract metadata
- T2 Amelioration of atherosclerotic complications and dyslipidemia by verbascoside-enriched fraction of Clerodendrum glandulosum leaves targeting LDL-R and LXR-mediated reverse cholesterol transport. literature abstract metadata
- T3 Clerodendrum glandulosum CC BY-SA 4.0