Bonnet Bellflower
Codonopsis
Codonopsis, a traditional Chinese medicinal plant, is rooted in East Asian medicine practices. It has been traditionally used for various purposes such as tonifying qi and enhancing overall health but specific uses are not extensively documented in historical records. Scientific evidence suggests potential benefits in improving heart failure outcomes, with different extracts showing distinct advantages; however, the evidence base remains limited for some interventions. Microscopic analysis and HPLC-UV methods have been effective in authenticating Codonopsis species and detecting adulterants. Additionally, studies indicate that Codonopsis pilosula polysaccharides may help ameliorate ulcerative colitis by activating AMPK-mediated mitophagy to inhibit the cGAS-STING inflammatory axis. Further, liquiritin from Codonopsis pilosula-Glycyrrhiza uralensis extract has been shown to potentially alleviate weaning stress in piglets through interactions with alpha-1-microglobulin/bikunin precursor. No major safety concerns or known drug interactions have been recorded for this plant.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that various plant extracts showed potential in improving heart failure outcomes, with different extracts offering distinct benefits, though evidence is limited for some interventions.
- Microscopic examination combined with HPLC-UV analysis effectively authenticated Panax species and detected common adulterants.
- Codonopsis pilosula polysaccharides from Shenling Baizhu Formula ameliorate DSS-induced ulcerative colitis by activating AMPK-mediated mitophagy to inhibit the cGAS-STING inflammatory axis.
- The study found that liquiritin from Codonopsis pilosula-Glycyrrhiza uralensis extract may alleviate weaning stress in piglets by interacting with alpha-1-microglobulin/bikunin precursor.
- Lobetyolin from Codonopsis Radix reinforces endothelial cytoskeletal integrity to alleviate Pseudomonas aeruginosa-induced acute lung injury by targeting α-actinin-1.
Frequently asked questions
What is Bonnet Bellflower?
Bonnet Bellflower (Codonopsis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bonnet Bellflower?
5 sourced findings are recorded for Bonnet Bellflower; the strongest carries evidence grade A. For example: The study found that various plant extracts showed potential in improving heart failure outcomes, with different extracts offering distinct benefits, though evidence is limited for some interventions.
How strong is the evidence for Bonnet Bellflower?
The strongest finding for Bonnet Bellflower carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Bonnet Bellflower safe? What are the side effects?
No major safety issues are recorded for Bonnet Bellflower in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bonnet Bellflower interact with medications?
No drug interactions are recorded for Bonnet Bellflower in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bonnet Bellflower?
Bonnet Bellflower is also known as: Кодонопсис.
Is Bonnet Bellflower a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Lobetyolin reinforces endothelial cytoskeletal integrity to alleviate Pseudomonas aeruginosa-induced acute lung injury via targeting ACTN1. literature abstract metadata
- T2 Codonopsis pilosula as the sovereign herb in Shenling Baizhu formula ameliorates DSS-induced ulcerative colitis via spermidine-AMPK-mediated mitophagy to inhibit the cGAS-STING inflammatory axis. literature abstract metadata
- T2 Mechanism of liquiritin from Codonopsis pilosula-Glycyrrhiza uralensis extract in alleviating piglet weaning stress via binding to alpha-1-microglobulin/bikunin precursor by machine learning and molecular dynamics simulation. literature abstract metadata
- T2 Microscopy Combined with LC-UV Analysis as a Tool for Authentication of Ginseng Species Used in Traditional Medicine and Detection of Their Adulterants. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata