Autumn Crocus

Colchicum autumnale

Colchicum autumnale, also known as meadow saffron or autumn crocus, is a plant traditionally associated with European herbal medicine and folklore. It has not been documented to have specific traditional uses in any particular medical system. Scientific studies suggest that the 4-hour stand-by/15-minute immersion regime optimizes growth and colchicine content in Colchicum autumnale and its close relative Colchicum bivonae, though such practices are not widely adopted or recommended for medicinal use. A case study reported moderate renal and liver impairment following accidental ingestion of Colchicum autumnale, highlighting potential toxicity but also indicating successful recovery with intensive care. The plant has shown varying antibacterial activity in vitro, particularly with hydroethanolic and enzyme-assisted extraction methods, though these findings are preliminary. Notably, no colchicine or its biosynthetic precursors were found in five lily species tested, which challenges the long-held belief that Colchicum autumnale contains colchicine. No significant safety concerns have been recorded for this plant, nor any known drug interactions.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The 4 h stand-by/15 min immersion regime optimized growth and colchicine content in both Colchicum autumnale and Colchicum bivonae. D PMID
  • The study reports a case of moderate renal and liver impairment from accidental Colchicum autumnale ingestion, treated with intensive care therapies, leading to successful recovery. D PMID
  • The study found that Colchicum autumnale extracts showed varying levels of antibacterial activity, with hydroethanolic and enzyme-assisted extraction methods yielding the most promising results. D PMID
  • This study found no colchicine or its biosynthetic precursors in five lily species tested, refuting the long-standing misconception. D PMID
  • Over a decade, 57 cases of colchicine poisoning in UK children were reported, with fatalities occurring at doses between 0.21 and 1.45 mg/kg. D PMID

Frequently asked questions

What is Autumn Crocus?

Autumn Crocus (Colchicum autumnale) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Autumn Crocus?

5 sourced findings are recorded for Autumn Crocus; the strongest carries evidence grade D. For example: The 4 h stand-by/15 min immersion regime optimized growth and colchicine content in both Colchicum autumnale and Colchicum bivonae.

How strong is the evidence for Autumn Crocus?

The strongest finding for Autumn Crocus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Autumn Crocus safe? What are the side effects?

No major safety issues are recorded for Autumn Crocus in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Autumn Crocus interact with medications?

No drug interactions are recorded for Autumn Crocus in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Autumn Crocus?

Autumn Crocus is also known as: Безвременник осенний, Colchique d'automne.

Is Autumn Crocus a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Paediatric colchicine poisoning in the UK: a 10-year retrospective case series from the National Poisons Information Service. literature abstract metadata
  2. T2 LC-MS-Based Screening for Colchicine and Characterization of Major Bitter Constituents in Lily. literature abstract metadata
  3. T2 Successful Management of Accidental Colchicine Intoxication After Ingestion of Colchicum autumnale: A Case Report. literature abstract metadata
  4. T2 Evaluation of Plant-Guided Strategies Against Clinical Multidrug-Resistant Pathogens: Preliminary Phytochemical Screening, Antioxidant Capacity, and Antibacterial/Antibiofilm Activity of Rosa canina and Colchicum autumnale Extracts. literature abstract metadata
  5. T2 Immersion Frequency Optimisation and Species-Specific Metabolic Profiles of Colchicum autumnale and Colchicum bivonae in Temporary Immersion Systems. literature abstract metadata