Hairy Thorn-apple
Datura wrightii
Datura wrightii, also known as sacred datura or jimsonweed, is a traditional plant native to North America. While its use in specific traditions has not been extensively documented, it is known for containing potent alkaloids such as scopolamine and atropine, which have historically been used for their medicinal properties, including pain relief and sedation. Scientific evidence suggests that Datura wrightii plays a significant role in plant-herbivore interactions. A study found thousands of genes differentially expressed between individuals feeding on Datura wrightii and Nicotiana attenuata, indicating its importance in ecological relationships. Additionally, the presence of elaiosomes (seed appendages) influences seed dispersal by ants, highlighting both benefits and costs to the plant. Moths that feed on nectar from this plant maintain healthy osmolality, but dehydration can lead to osmotic stress and reduced survival. Safety records for Datura wrightii show no major issues; however, due to its potent alkaloids, it is crucial to handle with care. There are currently no reported drug interactions associated with the use of Datura wrightii.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found thousands of genes differentially expressed between individuals feeding on Datura wrightii and Nicotiana attenuata.
- The study found over 3000 differentially expressed genes associated with herbivory in Datura wrightii.
- Ants removed Datura wrightii seeds with heavier elaiosomes and lighter seeds more quickly, supporting that both benefits and costs influence seed dispersal.
- Moths maintained healthy osmolality with nectar feeding, but dehydration led to osmotic stress and reduced survival.
Frequently asked questions
What is Hairy Thorn-apple?
Hairy Thorn-apple (Datura wrightii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hairy Thorn-apple?
4 sourced findings are recorded for Hairy Thorn-apple; the strongest carries evidence grade D. For example: The study found thousands of genes differentially expressed between individuals feeding on Datura wrightii and Nicotiana attenuata.
How strong is the evidence for Hairy Thorn-apple?
The strongest finding for Hairy Thorn-apple carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Hairy Thorn-apple safe? What are the side effects?
No major safety issues are recorded for Hairy Thorn-apple in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hairy Thorn-apple interact with medications?
No drug interactions are recorded for Hairy Thorn-apple in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hairy Thorn-apple?
Hairy Thorn-apple is also known as: Datura de Wright.
Is Hairy Thorn-apple a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A de novo long-read genome assembly of the sacred datura plant (Datura wrightii) reveals a role of tandem gene duplications in the evolution of herbivore-defense response. literature abstract metadata
- T2 A pooled-sample draft genome assembly provides insights into host plant-specific transcriptional responses of a Solanaceae-specializing pest, Tupiocoris notatus (Hemiptera: Miridae). literature abstract metadata
- T2 Dying of thirst: Osmoregulation by a hawkmoth pollinator in response to variability in ambient humidity and nectar availability. literature abstract metadata
- T2 Both costs and benefits determine the removal of Datura (Solanaceae) seeds by seed-dispersing ants. literature abstract metadata