derris
Derris elliptica
Derris elliptica, a plant traditionally used in some folk medicine practices but with no specific traditional uses documented, has shown potential in scientific research. Studies have indicated that its methanolic leaf extract may possess hypoglycemic and cytoprotective properties, comparable to glibenclamide, which is commonly used for diabetes management. Additionally, three new rotenoids isolated from the plant demonstrated anti-microbial activity against certain bacterial strains and fungi, while one compound exhibited concentration-dependent suppression of cell growth in tumor-derived cell lines. While the plant has been cited as a traditional remedy for fever and influenza, scientific evidence supporting these claims is limited. Safety concerns are currently minimal, with no major issues recorded; however, comprehensive safety data remains to be established. There have been no reported drug interactions, but further research is needed to fully understand its potential effects and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Derris elliptica methanolic leaf extract showed significant hypoglycemic effects and cytoprotective properties in STZ-induced diabetic rats, similar to glibenclamide.
- Three new rotenoids were isolated from Derris elliptica and showed anti-microbial activity against certain bacterial strains and fungi.
- Compound 3 from Derris elliptica showed concentration-dependent suppression of cell growth and increased cytotoxicity in several tumor-derived cell lines.
- Derris elliptica was cited by respondents for treating fever and influenza.
Frequently asked questions
What is derris?
derris (Derris elliptica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about derris?
4 sourced findings are recorded for derris; the strongest carries evidence grade D. For example: Derris elliptica methanolic leaf extract showed significant hypoglycemic effects and cytoprotective properties in STZ-induced diabetic rats, similar to glibenclamide.
How strong is the evidence for derris?
The strongest finding for derris carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is derris safe? What are the side effects?
No major safety issues are recorded for derris in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does derris interact with medications?
No drug interactions are recorded for derris in our sources. This does not rule them out — check with a pharmacist.
What are the common names of derris?
derris is also known as: Derris elliptique.
Is derris a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Ethnobotanical study of medicinal plants used by the Kenyah community of Borneo. literature abstract metadata
- T2 Three new rotenoids from the stems of Derris elliptica and their anti-microbial activity. literature abstract metadata
- T2 Exploring the therapeutic potential of Derris elliptica (Wall.) Benth in Streptozotocin-Induced diabetic Rats: Phytochemical characterization and antidiabetic evaluation. literature abstract metadata
- T2 13-Homo-13-oxa-6a, 12a-dehydrorotenoids from Derris elliptica. literature abstract metadata