Digitalis grandiflora
Digitalis grandiflora
Digitalis grandiflora is a plant native to Europe, particularly found in mountainous regions. Traditionally, its use has not been well-documented; however, it shares similar properties with other Digitalis species which have been used for their cardiac effects. Scientific evidence suggests that D. grandiflora contains compounds that may show potential therapeutic benefits, such as attenuating inflammation and apoptosis in LPS-induced acute respiratory distress syndrome (ARDS) in mice. Additionally, the plant has shown significant cytotoxicity against HEp-2 cells, indicating possible anti-cancer properties. While studies have identified new compounds from D. grandiflora, their specific effects are not extensively documented. Safety concerns for this plant do not appear to be major, and there is no recorded evidence of drug interactions; however, the use of any Digitalis species should proceed with caution due to their potent cardiac effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study reports on a mixed intoxication case involving monkshood and large yellow foxglove, showing that FAB antibodies can normalize heart rhythm in such cases.
- The study identified new compounds from Digitalis grandiflora and found that one showed significant cytotoxicity against HEp-2 cells.
- LG attenuated inflammation and apoptosis in LPS-induced ARDS in mice, suggesting potential therapeutic benefits.
- Flower corollae retained bee-derived nonacosenes for up to 24 hours, suggesting they can record visitation patterns.
- The study found that while there were differences in the chemical profiles between D. lanata, D. ferruginea, and D. grandiflora, quantitative variation within species was limited.
Frequently asked questions
What is Digitalis grandiflora?
Digitalis grandiflora (Digitalis grandiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Digitalis grandiflora?
5 sourced findings are recorded for Digitalis grandiflora; the strongest carries evidence grade D. For example: The study reports on a mixed intoxication case involving monkshood and large yellow foxglove, showing that FAB antibodies can normalize heart rhythm in such cases.
How strong is the evidence for Digitalis grandiflora?
The strongest finding for Digitalis grandiflora carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Digitalis grandiflora safe? What are the side effects?
No major safety issues are recorded for Digitalis grandiflora in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Digitalis grandiflora interact with medications?
No drug interactions are recorded for Digitalis grandiflora in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Digitalis grandiflora?
Digitalis grandiflora is also known as: Наперстянка крупноцветковая, Digitale à grandes fleurs.
Is Digitalis grandiflora a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Hydrocarbon footprints as a record of bumblebee flower visitation. literature abstract metadata
- T2 Mixed intoxication with Aconitum nappellans (monkshood) and Digitalis grandiflora (large yellow foxglove). literature abstract metadata
- T2 Lugrandoside attenuates LPS-induced acute respiratory distress syndrome by anti-inflammation and anti-apoptosis in mice. literature abstract metadata
- T2 New knowledge about old drugs; a cardenolide type glycoside with cytotoxic effect and unusual secondary metabolites from Digitalis grandiflora Miller. literature abstract metadata
- T2 Variation in the chemical profiles of three foxglove species in the central Balkans. literature abstract metadata