Digitalis
Digitalis lanata
Digitalis lanata is a plant traditionally used in various herbal practices but lacks specific recorded traditional uses. Scientific evidence suggests that compounds from this plant, particularly lanatoside C, may inhibit prostate cancer cell proliferation and induce apoptosis through modulation of the TNF/IL-17 signaling pathway. Additionally, Digitalis lanata has been studied for its anti-HIV properties within the context of traditional Chinese medicine, though comprehensive clinical trials are limited. The biosynthetic pathway for digoxin in this plant involves enzymes localized subcellularly as follows: P450scc and 3βHSD in the endoplasmic reticulum (ER) and cytosol, respectively, while P5βR2 is located in the cytosol. No significant safety concerns or major drug interactions have been recorded for Digitalis lanata to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Lanatoside C from Digitalis lanata inhibits prostate cancer cell proliferation and induces apoptosis through modulating the TNF/IL-17 signaling pathway.
- The study reviews 60 years of research on plant progesterone metabolism, highlighting known enzymes from Digitalis lanata and other species.
- Digitalis lanata is among the medicinal plants with anti-HIV properties considered in traditional Chinese medicine.
- The subcellular localizations of P450scc, 3βHSD, and P5βR2 in the digoxin biosynthetic pathway were identified as ER, cytosol, and cytosol, respectively.
- Digitalis lanata is among the natural products discussed for potential use in managing cardiovascular diseases.
Frequently asked questions
What is Digitalis?
Digitalis (Digitalis lanata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Digitalis?
5 sourced findings are recorded for Digitalis; the strongest carries evidence grade D. For example: Lanatoside C from Digitalis lanata inhibits prostate cancer cell proliferation and induces apoptosis through modulating the TNF/IL-17 signaling pathway.
How strong is the evidence for Digitalis?
The strongest finding for Digitalis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Digitalis safe? What are the side effects?
No major safety issues are recorded for Digitalis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Digitalis interact with medications?
No drug interactions are recorded for Digitalis in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Digitalis?
Digitalis is also known as: Наперстянка шерстистая, Digitale laineuse.
Is Digitalis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The Importance of Traditional Chinese Medicine in the Intervention and Treatment of HIV while Considering its Safety and Efficacy. literature abstract metadata
- T2 Progesterone Metabolism in Digitalis and Other Plants-60 Years of Research and Recent Results. literature abstract metadata
- T2 The Potential of Natural Products in the Management of Cardiovascular Disease. literature abstract metadata
- T2 Lanatoside C Inhibits Proliferation and Induces Apoptosis in Human Prostate Cancer Cells Through the TNF/IL-17 Signaling Pathway. literature abstract metadata
- T2 Subcellular localization of enzymes involved in the biosynthesis of digoxin in Digitalis lanata. literature abstract metadata