Entada rheedei
Entada rheedei
Entada rheedei, also known as the African bean or Dhaincha, is a plant traditionally found in tropical regions of Africa and Asia. While it has not been extensively used in traditional medicine practices, studies have shown potential biological activities such as anti-proliferation and melanogenesis inhibition. Scientific evidence indicates that two new tryptophan derivatives from Entada rheedei seed kernels promoted early HIV infection events by inhibiting indolamine 2,3-dioxygenase, though the findings are preliminary and require further investigation. Five new compounds, including triterpene oligoglycosides and a thioamide glycoside, were isolated from the seed kernels of Entada rheedei, but their specific effects remain to be fully elucidated. No major safety issues or drug interactions have been recorded for this plant, suggesting it may be generally safe when used appropriately.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study reviews potential biological activities, including anti-proliferation and melanogenesis inhibition, of Entada phaseoloides and E. rheedei seed kernels.
- The study isolated five new compounds and one known compound from Entada rheedei seed kernels.
- Four new triterpene oligoglycosides and one thioamide glycoside were isolated from Entada rheedei seed kernels.
- Two new tryptophan derivatives from Entada rheedei showed no toxicity to cells but promoted early HIV infection events by inhibiting indolamine 2,3-dioxygenase.
Frequently asked questions
What is Entada rheedei?
Entada rheedei (Entada rheedei) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Entada rheedei?
4 sourced findings are recorded for Entada rheedei; the strongest carries evidence grade D. For example: The study reviews potential biological activities, including anti-proliferation and melanogenesis inhibition, of Entada phaseoloides and E. rheedei seed kernels.
How strong is the evidence for Entada rheedei?
The strongest finding for Entada rheedei carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Entada rheedei safe? What are the side effects?
No major safety issues are recorded for Entada rheedei in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Entada rheedei interact with medications?
No drug interactions are recorded for Entada rheedei in our sources. This does not rule them out — check with a pharmacist.
Is Entada rheedei a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Medicinal plants of Thailand. I structures of rheedeiosides A-D and cis-entadamide A β-D-glucopyranoside from the seed kernels of Entada rheedei. literature abstract metadata
- T2 Medicinal plants of Thailand. II: chemical studies on the seed kernels of Entada rheedei Sprengel. literature abstract metadata
- T2 Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. literature abstract metadata
- T2 Biological activity of Entada phaseoloides and Entada rheedei. literature abstract metadata