Glycyrrhiza uralensis

Glycyrrhiza uralensis, also known as Chinese licorice or Urallic licorice, is a traditional medicinal plant used in East Asian and Tibetan medicine. Traditionally, it has been employed for its purported anti-inflammatory, antitussive, and immunomodulatory properties; however, specific uses vary across different traditions without clear documentation. Scientific evidence suggests that Piriformospora indica colonization can enhance the growth, stress resistance, and accumulation of medicinal compounds in G. uralensis under salt stress conditions. Additionally, partial organic fertilizer substitution has been shown to alter gene expression related to carbon and nitrogen cycling, influencing soil microbial functions and plant growth traits. In multiherb formulations, some have supported microbial balance and enhanced mucosal integrity, while others showed varied effects. Qishen paste improved cardiac conduction and function in heart failure mice by upregulating Cx43 in cardiac resident macrophages. No major safety issues or drug interactions have been recorded for G. uralensis; however, its use should be monitored due to the potential for glycyrrhizic acid-induced side effects such as hypertension and edema, especially at high doses.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.