Liquorice

Glycyrrhiza glabra, commonly known as licorice, is a traditional plant used in various herbal medicine practices. Its use spans multiple cultures and has historical significance, though specific traditional uses are not extensively documented. Scientific evidence suggests potential benefits for managing metabolic and inflammatory parameters in women with polycystic ovary syndrome (PCOS) and chronic respiratory conditions through its mucilage and iridoid compounds. There is also preliminary preclinical evidence indicating licorice's potential as a complementary approach for cognitive support and neuroprotection, though more extensive clinical studies are needed to confirm these findings. Licorice has shown promise in preserving cardiac mitochondrial redox homeostasis during estrogen deficiency by modulating monoamine oxidase-A (MAO-A) and estrogen receptor beta (ERβ). No major safety issues or recorded drug interactions have been identified for licorice, but its use should still be monitored due to the potential for side effects such as sodium retention and hypertension in high doses.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.