FolkKB

Gynura japonica

Gynura japonica

Gynura japonica, a plant native to Asia and traditionally used in some Asian herbal practices, has not been extensively documented for specific traditional uses. Scientific evidence is limited, but one study identified Gynura japonica consumption leading to misdiagnosis as pancreatitis due to hepatic sinusoidal obstruction syndrome (HSOS). Another study found that Gancao decoction, which includes Gynura japonica, improved serum biochemistry and hepatic histopathology in mice with HSOS by suppressing neutrophil chemotaxis and inhibiting senecionine bioactivation. Among 265 Traditional Chinese Medicine (TCM) cases of liver injury reported, Gynura japonica was among the plants involved. No major safety issues or drug interactions have been recorded for this plant.

At a glance
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • This study reports the first identification of apple stem grooving virus infecting Lilium brownii in China. D PMID
  • The study reports a case where Gynura japonica consumption led to misdiagnosis as pancreatitis before correct identification of hepatic sinusoidal obstruction syndrome. D PMID
  • Gancao decoction improved serum biochemistry and hepatic histopathology in senecionine-induced HSOS mice by suppressing neutrophil chemotaxis and inhibiting SEN bioactivation. D PMID
  • Gynura japonica was among the 265 TCMs reported in 571 cases of liver injury. D PMID

Frequently asked questions

What is Gynura japonica?

Gynura japonica (Gynura japonica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Gynura japonica?

4 sourced findings are recorded for Gynura japonica; the strongest carries evidence grade D. For example: This study reports the first identification of apple stem grooving virus infecting Lilium brownii in China.

How strong is the evidence for Gynura japonica?

The strongest finding for Gynura japonica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Gynura japonica safe? What are the side effects?

No major safety issues are recorded for Gynura japonica in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Gynura japonica interact with medications?

No drug interactions are recorded for Gynura japonica in our sources. This does not rule them out — check with a pharmacist.

Is Gynura japonica a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Review on traditional Chinese medicine-induced liver injury. literature abstract metadata
  2. T2 Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver. literature abstract metadata
  3. T2 Hepatic sinusoidal obstruction syndrome caused by Gynura japonica once misdiagnosed as pancreatitis: a case report and review of literature. literature abstract metadata
  4. T2 First report of apple stem grooving virus infecting a species of Lilium (Lilium brownii) in China. literature abstract metadata

More Gynura plants