Longevity spinach
Gynura procumbens
Gynura procumbens is a plant traditionally used in various folk remedies but lacks specific documented traditional uses. Scientific research indicates that its stem extract and phenolic compounds, particularly scopoletin, exhibit significant antioxidant and anti-inflammatory effects, potentially through the inhibition of MAPK/NF-κB pathways. The plant also shows promise in modulating inflammation and lipid metabolism related to diabetic kidney disease. Computational analysis suggests luteolin from Gynura procumbens may inhibit MMP9 in non-small cell lung cancer (NSCLC). Additionally, it has been observed that the extract can increase VEGF expression and improve wound healing in diabetic rats, with optimal results at 300 mg/kg body weight. No major safety issues or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study suggests that Gynura procumbens may modulate inflammatory and lipid metabolic pathways in diabetic kidney disease.
- The study found that Gynura procumbens stem extract and its phenolic compounds, particularly scopoletin, have significant antioxidant and anti-inflammatory effects through MAPK/NF-κB pathway inhibition.
- The study found that luteolin from Gynura procumbens showed potential as an inhibitor of MMP9 in NSCLC through computational analysis.
- Gynura procumbens extract increased VEGF expression and improved wound healing in diabetic rats, with the best results at 300 mg/kg body weight.
- Ultrasound treatment for 10 minutes enhanced the phytochemical content of Gynura procumbens leaves, showing potential in preventing muscle atrophy.
Frequently asked questions
What is Longevity spinach?
Longevity spinach (Gynura procumbens) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Longevity spinach?
5 sourced findings are recorded for Longevity spinach; the strongest carries evidence grade D. For example: This study suggests that Gynura procumbens may modulate inflammatory and lipid metabolic pathways in diabetic kidney disease.
How strong is the evidence for Longevity spinach?
The strongest finding for Longevity spinach carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Longevity spinach safe? What are the side effects?
No major safety issues are recorded for Longevity spinach in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Longevity spinach interact with medications?
No drug interactions are recorded for Longevity spinach in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Longevity spinach?
Longevity spinach is also known as: Гинура распростёртая.
Is Longevity spinach a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effect of post-harvest ultrasound treatment on phytochemical enhancement in Gynura procumbens leaves and their protection against oxidative stress-induced muscle atrophy. literature abstract metadata
- T2 Gynura procumbens Modulates VEGF Expression in Diabetic Wounds: Evidence from Immunohistochemistry and in silico Analysis. literature abstract metadata
- T2 Exploration of network-based, machine learning, MD simulations, and MM/GBSA approaches revealed luteolin from Gynura procumbens as key inhibitor of MMP9 in NSCLC. literature abstract metadata
- T2 Investigation of the Potential Anti-Diabetic Kidney Disease Mechanism of Gynura procumbens (Lour.) Merr via Transcriptomics Combined With Network Pharmacology. literature abstract metadata
- T2 Binding affinity screening and MAPK/NF-κB mechanisms of antioxidant and anti-inflammatory phenolics compounds from Gynura procumbens stem extract (GPSE). literature abstract metadata