Hypericum hirsutum
Hypericum hirsutum
Hypericum hirsutum is a plant traditionally not associated with any specific medicinal use. Scientific studies have identified 19 novel acylphloroglucinols from this species, some of which showed moderate activity in reducing cell proliferation and ICAM-1 expression, while amentoflavone inhibited benzodiazepine binding in vitro. Other constituents did not demonstrate significant activity. The essential oil composition varied, primarily containing alkanes, but no significant antifungal properties were observed. Positive correlations between hypericin and putative precursors suggest a shared biosynthetic pathway. No major safety issues or drug interactions have been recorded for Hypericum hirsutum to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 19 novel acylphloroglucinols from Hypericum hirsutum, including homoadamantane and adamantane scaffolds, showing moderate activity in reducing cell proliferation and ICAM-1 expression.
- Amentoflavone inhibited benzodiazepine binding in vitro, while other constituents did not show significant activity.
- A significant positive correlation between hypericin and putative precursors such as pseudohypericin and emodin was observed.
- The essential oil composition of Hypericum hirsutum varied, containing alkanes as the main class, and showed no significant antifungal activity.
Frequently asked questions
What is Hypericum hirsutum?
Hypericum hirsutum (Hypericum hirsutum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hypericum hirsutum?
4 sourced findings are recorded for Hypericum hirsutum; the strongest carries evidence grade D. For example: The study identified 19 novel acylphloroglucinols from Hypericum hirsutum, including homoadamantane and adamantane scaffolds, showing moderate activity in reducing cell proliferation and ICAM-1 expression.
How strong is the evidence for Hypericum hirsutum?
The strongest finding for Hypericum hirsutum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Hypericum hirsutum safe? What are the side effects?
No major safety issues are recorded for Hypericum hirsutum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hypericum hirsutum interact with medications?
No drug interactions are recorded for Hypericum hirsutum in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hypericum hirsutum?
Hypericum hirsutum is also known as: Зверобой жестковолосый, Millepertuis hérissé.
Is Hypericum hirsutum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum. literature abstract metadata
- T2 Homoadamantane and Adamantane Acylphloroglucinols from Hypericum hirsutum. literature abstract metadata
- T2 Essential Oil Composition of Seven Bulgarian Hypericum Species and Its Potential as a Biopesticide. literature abstract metadata
- T2 Inhibition of benzodiazepine binding in vitro by amentoflavone, a constituent of various species of Hypericum. literature abstract metadata