Curled-leaved St. John's-wort
Hypericum triquetrifolium
Hypericum triquetrifolium is a plant native to Europe and Asia. While its traditional use in folk medicine has not been extensively documented, studies have shown promising results for its potential health benefits. Scientific evidence indicates that hydroalcoholic extracts of Hypericum triquetrifolium exhibit strong antioxidant and anti-inflammatory properties, with selective cytotoxicity against pancreatic cancer cells. However, the plant does not show significant antimicrobial or general cytotoxic activity. The essential oil and aroma contents from 21 different locations revealed moderate antioxidant capacity but varied in specific compound content. Safety profiles for Hypericum triquetrifolium are currently favorable, with no major issues recorded. There is also no evidence of drug interactions at this time.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Hypericum triquetrifolium hydroalcoholic extract shows strong antioxidant and anti-inflammatory activity, with selective cytotoxicity against pancreatic cancer cells.
- Hypericum triquetrifolium displayed no significant antimicrobial or cytotoxic activity in this study.
- The essential oil and aroma contents of Hypericum triquetrifolium from 21 different locations were analyzed, revealing moderate antioxidant capacity and varying levels of cholinesterase, tyrosinase, and urease inhibition.
- The study found that Hypericum species extracts and key components showed varying degrees of enzyme inhibition and antioxidant activity.
Frequently asked questions
What is Curled-leaved St. John's-wort?
Curled-leaved St. John's-wort (Hypericum triquetrifolium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Curled-leaved St. John's-wort?
4 sourced findings are recorded for Curled-leaved St. John's-wort; the strongest carries evidence grade D. For example: Hypericum triquetrifolium hydroalcoholic extract shows strong antioxidant and anti-inflammatory activity, with selective cytotoxicity against pancreatic cancer cells.
How strong is the evidence for Curled-leaved St. John's-wort?
The strongest finding for Curled-leaved St. John's-wort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Curled-leaved St. John's-wort safe? What are the side effects?
No major safety issues are recorded for Curled-leaved St. John's-wort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Curled-leaved St. John's-wort interact with medications?
No drug interactions are recorded for Curled-leaved St. John's-wort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Curled-leaved St. John's-wort?
Curled-leaved St. John's-wort is also known as: Зверобой трёхграннолистный, Millepertuis.
Is Curled-leaved St. John's-wort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Screening of Antimicrobial, Antibiofilm, and Cytotoxic Activities of Some Medicinal Plants from Balıkesir Province, Türkiye: Potential Effects of Allium paniculatum Flower. literature abstract metadata
- T2 In Vitro and In Silico Studies on Unique Key Components of Hypericum Species, Focusing on Their Role in Inhibiting Enzymatic Pathways. literature abstract metadata
- T2 Detailed Chemical Investigation of the Essential Oil and Aroma Contents of 21 Hypericum triquetrifolium Turra Species Collected From Different Localities via a Chemometric Approach. literature abstract metadata
- T2 In Vitro Evidence for the Dual Antioxidant and Anti-Inflammatory Roles of Hypericum triquetrifolium in Cancer Therapy: Selective Cytotoxicity Against Pancreatic Cancer Cells. literature abstract metadata