Chinese motherwort

Leonurus japonicus, commonly known as motherwort, is a traditional herb primarily used in East Asian medicine. While its specific uses are not well-documented, it has been traditionally employed for various conditions including menstrual disorders and cardiovascular issues. Scientific evidence suggests that Leonurus japonicus extract and leonurine may improve muscle recovery by activating the PI3K/Akt/mTOR pathway and reducing proteolysis, though more research is needed to confirm these findings. Additionally, studies indicate that leonurine can inhibit renal cell carcinoma proliferation and migration while inducing apoptosis through targeting the PDK1-mediated Warburg effect. The herb also shows multi-targeted therapeutic potential in cardiovascular, oncology, renal, gynecological, and inflammatory disorders, as documented by a systematic review. Notably, modified biochars from Leonurus japonicus have been found to enhance Cu(II) adsorption capacities compared to unmodified biochars, with retained effectiveness after multiple cycles. No major safety issues or recorded drug interactions are currently known for Leonurus japonicus.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.