Chinese motherwort
Leonurus japonicus
Leonurus japonicus is a traditional Chinese medicinal plant. While its specific uses in traditional medicine are not well-documented, studies have shown potential benefits for muscle recovery and cancer inhibition. Research indicates that Leonurus japonicus extract and leonurine can improve muscle recovery by activating the PI3K/Akt/mTOR pathway and reducing proteolysis in mice. Additionally, leonurine has been found to inhibit renal cell carcinoma proliferation and migration by targeting the PDK1-mediated Warburg effect, with significant in vivo tumor growth restriction. A systematic review suggests that stachydrine, a compound from Leonurus japonicus, may have multi-targeted therapeutic potential across various conditions including cardiovascular, oncology, renal, gynecological, and inflammatory disorders. Notably, modified biochars derived from this plant showed enhanced Cu(II) adsorption capacities compared to unmodified biochars, with retained effectiveness after multiple cycles. Safety-wise, no major issues have been recorded for Leonurus japonicus. There are also no reported drug interactions associated with its use.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Leonurus japonicus extract and leonurine improved muscle recovery by activating the PI3K/Akt/mTOR pathway and reducing proteolysis in mice.
- Leonurine inhibited renal cell carcinoma proliferation and migration by targeting the PDK1-mediated Warburg effect, with significant in vivo tumor growth restriction.
- This systematic review documents stachydrine's multi-targeted therapeutic potential across cardiovascular, oncology, renal, gynecological, and inflammatory disorders.
- The study found that modified biochars from Leonurus japonicus showed enhanced Cu(II) adsorption capacities compared to unmodified biochars, with retained effectiveness after multiple cycles.
Frequently asked questions
What is Chinese motherwort?
Chinese motherwort (Leonurus japonicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese motherwort?
4 sourced findings are recorded for Chinese motherwort; the strongest carries evidence grade A. For example: Leonurus japonicus extract and leonurine improved muscle recovery by activating the PI3K/Akt/mTOR pathway and reducing proteolysis in mice.
How strong is the evidence for Chinese motherwort?
The strongest finding for Chinese motherwort carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese motherwort safe? What are the side effects?
No major safety issues are recorded for Chinese motherwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese motherwort interact with medications?
No drug interactions are recorded for Chinese motherwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese motherwort?
Chinese motherwort is also known as: Agripaume du Japon, Marie-Thérèse, Gros tombé, Herbe tombé rose.
Is Chinese motherwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Stachydrine: A Systematic Review of Its Multi-Targeted Therapeutic Potential in Cardiovascular, Oncology, Renal, Gynecological, and Inflammatory Disorders. literature abstract metadata
- T2 Efficient adsorption of Cu(II) from wastewater via modified biochars from residues of Chinese herbal medicines Pueraria lobata and Leonurus japonicus and direct reuses for electrode materials. literature abstract metadata
- T2 Leonurine suppresses renal cell carcinoma progression by targeting the PDK1-mediated Warburg effect. literature abstract metadata
- T2 Leonurine-Standardized Leonurus japonicus Extract Promotes Recovery from Immobilization-Induced Muscle Atrophy via PI3K/Akt/mTOR Signaling in Mice. literature abstract metadata