Honeyweed

Leonurus sibiricus

Leonurus sibiricus is a plant species featured in various traditional medicine practices. It has been historically utilized for a wide range of conditions, including fever, abscesses, boils, diarrhea, gynecopathy, hemorrhage, and edema. Preliminary scientific evidence suggests potential therapeutic properties, as certain isolated compounds have demonstrated anti-inflammatory activity and modulation of signaling pathways in laboratory settings. Additionally, silver nanoconjugates derived from the plant have shown antimicrobial and anti-biofilm activity against specific bacteria in vitro. No major safety issues or notable drug interactions have been recorded in current literature.

At a glance
Traditionally for
diuretic · fever
Traditions
TCM · Japanese (Kampo) · traditional
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • Compound 1 from Leonurus sibiricus showed potent inhibition of inflammatory markers and modulation of MAPK signaling pathway. D PMID
  • Both Leonurus sibiricus and Tinospora cordifolia-derived silver nanoconjugates showed antimicrobial and anti-biofilm activities against Pseudomonas aeruginosa, with TC-AgNPs being more effective. D PMID
  • Eleven labdane diterpenoids were isolated from Leonurus sibiricus, and sibiricusin O showed anti-inflammatory activity. D PMID
  • The complete chloroplast genome of Leonurus sibiricus has been sequenced, providing insights into its structure and phylogenetic relationships. D PMID

Frequently asked questions

What is Honeyweed?

Honeyweed (Leonurus sibiricus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Honeyweed traditionally used for?

Traditional sources record Honeyweed for: diuretic, fever, abscess, bleeding, boils, dropsy (edema). This reflects traditional use, not a proven medical treatment.

Which traditions use Honeyweed?

Honeyweed appears in these traditions in our sources: TCM, Japanese (Kampo), traditional.

What does the scientific evidence say about Honeyweed?

4 sourced findings are recorded for Honeyweed; the strongest carries evidence grade D. For example: Compound 1 from Leonurus sibiricus showed potent inhibition of inflammatory markers and modulation of MAPK signaling pathway.

How strong is the evidence for Honeyweed?

The strongest finding for Honeyweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Honeyweed safe? What are the side effects?

No major safety issues are recorded for Honeyweed in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Honeyweed interact with medications?

No drug interactions are recorded for Honeyweed in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Honeyweed?

Honeyweed is also known as: Agripaume de Sibérie.

Is Honeyweed a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Anti-inflammatory labdane diterpenoids from the aerial parts of Leonurus sibiricus. literature abstract metadata
  3. T2 The complete chloroplast genome of Leonurus sibiricus Linnaeus (Labiatae, Leonurus Miller). literature abstract metadata
  4. T2 Anti-Inflammatory Activity of Labdane and Norlabdane Diterpenoids from Leonurus sibiricus Related to Modulation of MAPKs Signaling Pathway. literature abstract metadata
  5. T2 Comparative evaluation of the bactericidal activities of two indigenous weed-derived silver nanoconjugates on planktonic and sessile forms of Pseudomonas aeruginosa: Antimicrobial and antibiofilm activities of weed-derived silver nanoconjug literature abstract metadata