Lycopus virginicus
Lycopus virginicus
Lycopus virginicus, commonly known as American bugleweed or Virginia bugloss, is a traditional medicinal plant native to North America. While it has been used in folk medicine for various purposes, no specific traditional uses have been recorded. Scientific studies indicate that flavone glucuronides from Lycopus virginicus, including apigenin, acacetin, and luteolin, show potential activity against thyroid-related conditions, with freeze-dried extracts demonstrating inhibition of Graves' immunoglobulins and thyrotropin binding to human thyroid membranes in a dose-dependent manner. However, the evidence is limited and more research is needed to confirm these findings. No major safety concerns or drug interactions have been reported for Lycopus virginicus, but further investigation is warranted given its potential therapeutic effects on thyroid function.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Flavone glucuronides of apigenin, acacetin, luteolin, and their methyl ester were isolated from Lycopus virginicus, with varying concentrations found in related species.
- Freeze-dried extracts and auto-oxidized constituents of Lycopus virginicus inhibited the binding and biological activity of Graves' immunoglobulins in a dose-dependent manner.
- Lycopus virginicus extracts inhibited the binding of bovine thyrotropin to human thyroid membranes in a dose-related manner.
- Lycopus virginicus extracts inhibit iodothyronine deiodinase activities in rat liver microsomes, varying by plant species and extraction method.
Frequently asked questions
What is Lycopus virginicus?
Lycopus virginicus (Lycopus virginicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lycopus virginicus?
4 sourced findings are recorded for Lycopus virginicus; the strongest carries evidence grade D. For example: Flavone glucuronides of apigenin, acacetin, luteolin, and their methyl ester were isolated from Lycopus virginicus, with varying concentrations found in related species.
How strong is the evidence for Lycopus virginicus?
The strongest finding for Lycopus virginicus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lycopus virginicus safe? What are the side effects?
No major safety issues are recorded for Lycopus virginicus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lycopus virginicus interact with medications?
No drug interactions are recorded for Lycopus virginicus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lycopus virginicus?
Lycopus virginicus is also known as: Зюзник виргинский.
Is Lycopus virginicus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Flavone glucuronides of Lycopus virginicus. literature abstract metadata
- T2 Extracts and auto-oxidized constituents of certain plants inhibit the receptor-binding and the biological activity of Graves' immunoglobulins. literature abstract metadata
- T2 Antihormonal effects of plant extracts: iodothyronine deiodinase of rat liver is inhibited by extracts and secondary metabolites of plants. literature abstract metadata
- T2 Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. literature abstract metadata