Chinese corktree
Phellodendron chinense
Phellodendron chinense, a plant traditionally used in traditional Chinese medicine (TCM), has not been documented for specific uses. Scientific evidence suggests potential benefits including significant decreases in breast nucleus diameter, uterine volume, ovarian volume, and follicular volume in females with precocious puberty. Additionally, the herb showed promise in type 2 diabetes mellitus by differentially expressing eight mitochondria-related genes. In sepsis-induced coagulopathy rats, Phellodendron chinense (HLJDD) improved coagulation dysfunction and reduced inflammatory responses, with estrogen receptor alpha (ESR1) identified as a key target. Furthermore, it demonstrated anti-inflammatory effects in an imiquimod-induced mouse model of psoriasis by reducing inflammatory mediator levels and histopathological damage. No major safety concerns or recorded drug interactions have been noted for Phellodendron chinense to date.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified eight mitochondria-related differentially expressed genes associated with Phellodendron chinense treatment in type 2 diabetes mellitus.
- HLJDD improved coagulation dysfunction and reduced inflammatory response in sepsis-induced coagulopathy rats, with ESR1 identified as a key target.
- PCC-CDs reduced inflammatory mediator levels and histopathological damage in an imiquimod-induced mouse model of psoriasis.
- CHM significantly decreased breast nucleus diameter, uterine volume, ovarian volume, and follicular volume in females with precocious puberty.
Frequently asked questions
What is Chinese corktree?
Chinese corktree (Phellodendron chinense) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese corktree?
4 sourced findings are recorded for Chinese corktree; the strongest carries evidence grade A. For example: The study identified eight mitochondria-related differentially expressed genes associated with Phellodendron chinense treatment in type 2 diabetes mellitus.
How strong is the evidence for Chinese corktree?
The strongest finding for Chinese corktree carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese corktree safe? What are the side effects?
No major safety issues are recorded for Chinese corktree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese corktree interact with medications?
No drug interactions are recorded for Chinese corktree in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese corktree?
Chinese corktree is also known as: Бархат китайский.
Is Chinese corktree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effect of Chinese herbal medicine on sexual characteristics of females with precocious puberty: a meta-analysis. literature abstract metadata
- T2 Enhancement of Psoriasis Treatment by Phellodendri Chinensis Cortex Carbon Dots (PCC-CDs) Through Modulation of the HMGB1/TLR4/MAPK/NF-κB Pathway. literature abstract metadata
- T2 Integrated network pharmacology and AlphaFold modeling reveal ESR1 as a key target of Huanglian Jiedu decoction for ameliorating sepsis-induced coagulopathy. literature abstract metadata
- T2 Identification of mitochondria-related key genes in type 2 diabetes mellitus and elucidation of the Zhimu-Huangbai herb Pair's mechanism: an integrated approach of bioinformatics, machine learning, and experimental validation. literature abstract metadata